An Jae Young, Park Min Su, Kim Joong Seok, Shon Young Min, Lee Seung Jae, Kim Yeong In, Lee Kwang Soo, Kim Byoung Joon
Department of Neurology, The Catholic University of Korea, Seoul.
Intern Med. 2008;47(15):1395-8. doi: 10.2169/internalmedicine.47.0901. Epub 2008 Aug 1.
Diabetic Neuropathy Symptom (DNS) scoring and medial plantar NCS are useful methods for diagnosis of diabetic polyneuropathy (DPN). We evaluated the correlation between DNS score and medial plantar NCS in diabetic patients with a normal routine NCS.
Nineteen healthy subjects were included as a control group. Fifty patients with diabetes mellitus who were referred for the evaluation of DPN were recruited (35 asymptomatic and 15 symptomatic). Control subjects and diabetic patients over the age of 70 were excluded from this study.
Medial plantar nerve action potential (NAP) was recordable in all 19 control subjects and was not obtainable in 7 out of 15 symptomatic patients and in 5 out of 35 asymptomatic patients. The amplitudes of sural (Spearman r=-0.293, p=0.003) and medial plantar NAP (Spearman r=-0.215, p=0.03) correlated with DNS score.
An abnormality finding in the medial plantar sensory nerve conduction study is a more sensitive indicator than sural nerve conduction study in the diagnosis of DPN and the medial plantar sensory nerve should be included in the evaluation of DPN in patients showing normal routine NCS.
糖尿病神经病变症状（DNS）评分和足底内侧神经传导速度（NCS）是诊断糖尿病性多发性神经病变（DPN）的有用方法。我们评估了常规NCS正常的糖尿病患者中DNS评分与足底内侧NCS之间的相关性。
纳入19名健康受试者作为对照组。招募了50名因DPN评估而转诊的糖尿病患者（35名无症状，15名有症状）。本研究排除了70岁以上的对照受试者和糖尿病患者。
在所有19名对照受试者中均可记录到足底内侧神经动作电位（NAP），15名有症状患者中有7名以及35名无症状患者中有5名无法获得该电位。腓肠神经（Spearman r = -0.293，p = 0.003）和足底内侧NAP（Spearman r = -0.215，p = 0.03）的波幅与DNS评分相关。
在DPN诊断中，足底内侧感觉神经传导研究中的异常发现比腓肠神经传导研究更敏感，在常规NCS正常的患者中，足底内侧感觉神经应纳入DPN评估。
