Ryou Kyoung Soo, Lee Sun-Ho, Park Seong-Hyun, Park Jaechan, Hwang Sung-Kyoo, Hamm In-Suk
Department of Neurosurgery, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
J Neurosurg. 2008 Aug;109(2):318-20. doi: 10.3171/JNS/2008/109/8/0318.
Carney complex is a rare autosomal-dominant familial tumor syndrome that involves the triad of myxoma, mucocutaneous pigmentation, and endocrine overactivity. To the best of the authors' knowledge, there are no reports of multiple fusiform aneurysms coinciding with atrial myxoma. The authors report the case of a 38-year-old woman with typical Carney complex who had multiple skin myxomas, endocrine abnormalities, and multiple brownish perioral lesions. Multiple fusiform aneurysms were also discovered after the recurrence of atrial myxoma. During a follow-up period of > 10 years, there have been no angiographic changes in the aneurysms and no progression of symptoms.
卡尼综合征是一种罕见的常染色体显性遗传性家族性肿瘤综合征,其特征为黏液瘤、黏膜皮肤色素沉着和内分泌功能亢进三联征。据作者所知,尚无多发性梭形动脉瘤与心房黏液瘤同时存在的报道。作者报告了一例38岁患有典型卡尼综合征的女性病例,该患者有多发皮肤黏液瘤、内分泌异常以及口周多发褐色病变。心房黏液瘤复发后还发现了多发性梭形动脉瘤。在超过10年的随访期内,动脉瘤的血管造影没有变化,症状也没有进展。