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[伴有脑渗透性动脉瘤的左心房黏液瘤,特别提及连续血管造影的重要性]

[Left atrial myxoma with cerebral oncotic aneurysms with special reference to the importance of serial angiography].

作者信息

Iihara K, Kikuchi H, Nagata I

机构信息

Department of Neurosurgery, Kyoto University Faculty of Medicine.

出版信息

No Shinkei Geka. 1991 Sep;19(9):857-60.

PMID:1944795
Abstract

A case of atrial myxoma with cerebral oncotic aneurysms was presented. A 37 year-old woman was admitted complaining of right hemiparesis, and episodes of syncope. Neurological examination on admission revealed a right arm monoparesis, a right hemisensory disturbance, and a motor aphasia. Computed tomography (CT) demonstrated low density areas in the left fronto-parietal region, and multiple discrete enhancing high density spots scattered bilaterally in the parietal lobes. Cerebral angiography showed multiple fusiform peripheral aneurysms especially in the distribution of the bilateral middle cerebral arteries. Cerebral emboli from the cardiac source were suspected, and an echocardiography was performed, which disclosed a huge villous mass in the left atrium. The cardiac mass was resected uneventfully under cardiopulmonary bypass. It proved to be a left atrial myxoma. Postoperatively, her neurological deficit persisted. After the resection of the cardiac tumor, follow-up angiographies were undertaken twice. The second angiography performed 6 months later revealed spontaneous resolution or stabilization of most of the aneurysms detected before. On the other hand, newly-developed aneurysms were seen at the sites which had seemed normal previously on the first angiography. No remarkable changes were seen on the third one except the slight enlargement of one of the aneurysms in the middle cerebral territory. At 3 years she was neurologically stable. Because of the paucity of knowledge concerning the natural history of cerebral oncotic aneurysms and lack of definite treatment for them, long-term follow-up including serial angiography is mandatory after the resection of left atrial myxoma.

摘要

本文报告一例伴有脑渗透性动脉瘤的心房黏液瘤病例。一名37岁女性因右侧偏瘫和晕厥发作入院。入院时神经系统检查发现右臂单瘫、右侧半身感觉障碍和运动性失语。计算机断层扫描(CT)显示左额顶叶区域有低密度区,双侧顶叶有多个散在的强化高密度斑点。脑血管造影显示多个梭形外周动脉瘤,尤其是在双侧大脑中动脉分布区。怀疑有心脏来源的脑栓塞,遂进行超声心动图检查,发现左心房有一个巨大的绒毛状肿块。在体外循环下顺利切除心脏肿块,病理证实为左心房黏液瘤。术后,她的神经功能缺损持续存在。切除心脏肿瘤后,进行了两次随访血管造影。6个月后进行的第二次血管造影显示,之前检测到的大多数动脉瘤自发消退或稳定。另一方面,在第一次血管造影时看似正常的部位出现了新的动脉瘤。第三次血管造影除大脑中动脉区域的一个动脉瘤略有增大外,未见明显变化。3年后她的神经功能稳定。由于对脑渗透性动脉瘤的自然病史了解不足,且缺乏明确的治疗方法,因此在切除左心房黏液瘤后必须进行包括系列血管造影在内的长期随访。

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Radiol Case Rep. 2018 Jan 2;13(2):490-494. doi: 10.1016/j.radcr.2017.11.015. eCollection 2018 Apr.
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Myxomatous aneurysms: a case report and literature review.黏液瘤样动脉瘤:一例病例报告及文献综述
Interv Neuroradiol. 2011 Jun;17(2):188-94. doi: 10.1177/159101991101700208. Epub 2011 Jun 20.