Isolated ACTH deficiency and pregnancy.

Isolated deficiences of anterior pituitary hormones are rare. A patient is presented whose hypoglycemia during pregnancy resulted from ACTH deficiency. Glucocorticoid treatment enabled her to complete pregnancy successfully. In addition, she did not menstruate during an interval in which she did not receive glucocorticoid therapy. The dynamics of fetal and maternal glucose metabolism are discussed as well as menstruation and fertility in adrenal insufficiency.