Javier Navarro F, Cozar J M, Nistal M, Martínez-Piñeiro L, Moreno J A, Jiménez J, Cisneros J, de la Peña J, Martínez-Piñeiro J A
Servicio Urología, Hospital La Paz, Facultad de Medicina, Universidad Autónoma, Madrid, España.
Arch Esp Urol. 1991 Mar;44(2):145-50.
Three cases of Leydig cell tumor are described. Patient ages were 27, 44 and 55 years, respectively. The first two patients consulted for a testicular mass and the third patient presented with gynecomastia, an incidental finding during the ultrasound work up of a hydrocele. Hormonal evaluation revealed a marked serum testosterone level in one case, whereas in another case it fell within the lower limits of normal ranges. No evidence of dissemination was observed in all patients. Treatment was by radical inguinal orchiectomy in all patients. The pathological analysis of the surgical specimens revealed Leydig cell tumor with no histologic evidence of malignancy. A follow-up of 32, 14 and 10 months, respectively, revealed no evidence of tumor recurrence in all patients. The clinical and histologic features and treatment of this disease process are described.
本文描述了三例莱迪希细胞瘤病例。患者年龄分别为27岁、44岁和55岁。前两名患者因睾丸肿块前来就诊,第三名患者因男性乳房发育症就诊,这是在鞘膜积液超声检查时偶然发现的。激素评估显示,其中一例患者血清睾酮水平显著升高,而另一例患者的血清睾酮水平则在正常范围下限。所有患者均未发现转移迹象。所有患者均接受了根治性腹股沟睾丸切除术。手术标本的病理分析显示为莱迪希细胞瘤,无恶性组织学证据。分别对患者进行了32个月、14个月和10个月的随访,结果显示所有患者均无肿瘤复发迹象。本文还描述了该疾病过程的临床和组织学特征及治疗方法。