Belin C, Faure S, Mayer E
UF Mémoire et Maladies Neurodégénératives, Service de Neurologie, CHU Avicenne, AP-HP, 125 route de Stalingrad, 93009 Bobigny cedex, France.
Rev Neurol (Paris). 2008 May;164 Suppl 3:S148-53. doi: 10.1016/S0035-3787(08)73306-X.
The first part of this article covers the main discoveries that led to the concept of hemispheric specialisation, from Egyptian antiquity to present times, through the pivotal XIXth century period that saw the attribution of specific cognitive functions to the left and right hemispheres. Next, this dichotomous conception of cerebral function, attributing a given process to a hemisphere and hypothesising callosal transmission, is discussed in the light of recent studies on language comprehension. Present day knowledge suggesting an alternative to the structuralist view of hemispheric specialisation in the form of dynamic, complementary sharing of labour, and of cooperation through transcortical neural networks, is then considered. Finally, the role of the corpus callosum in interhemispheric communication is briefly covered. An emphasis is placed on the diversity of this structure that is at the origin of highly different functions (fibre size, homotopic vs heterotopic connections). Ultimately, we contrast the view of a corpus callosum serving as an information transmitting channel with that of a fibre tract co-activating the non-engaged hemisphere and preparing it for potential stimulation. In this manner, the corpus callosum minimises disparities in the distribution of attention between the two hemispheres.
本文的第一部分涵盖了从埃及古代到现代,导致半球特化概念的主要发现,历经了19世纪这一关键时期,当时人们将特定的认知功能归因于左半球和右半球。接下来,鉴于最近关于语言理解的研究,对这种将特定过程归因于一个半球并假设胼胝体传递的二分法脑功能概念进行了讨论。然后考虑了当今的知识,这些知识以动态、互补的分工形式以及通过跨皮质神经网络的合作,为半球特化的结构主义观点提供了一种替代方案。最后,简要介绍了胼胝体在半球间通信中的作用。重点强调了这种结构的多样性,它是高度不同功能(纤维大小、同型与异型连接)的起源。最终,我们将胼胝体作为信息传输通道的观点与纤维束共同激活未参与半球并使其为潜在刺激做好准备的观点进行了对比。通过这种方式,胼胝体最大限度地减少了两个半球之间注意力分配的差异。