Fulka Josef, Fulka Helena, St John Justin, Galli Cesare, Lazzari Giovanna, Lagutina Irina, Fulka Josef, Loi Pasqualino
Institute of Animal Science, Prague, Czech Republic.
Trends Biotechnol. 2008 Sep;26(9):469-74. doi: 10.1016/j.tibtech.2008.06.001. Epub 2008 Jul 31.
The recent vote in the British Parliament allows scientists in principle to create hybrid embryos by transferring human somatic cell nuclei into animal oocytes. This vote opens a fascinating new area of research with the central aim of generating interspecific lines of embryonic stem cells (ESCs) that could potentially be used to understand development, differentiation, gene expression and genomic compatibility. It will also promote human cell therapies, as well as the pharmaceutical industry's search for new drug targets. If this approach is to be successful, many biological questions need to be answered and, in addition, some moral and ethical aspects must be taken into account.
英国议会近期的投票原则上允许科学家通过将人类体细胞核移植到动物卵母细胞中来制造杂交胚胎。这次投票开启了一个迷人的新研究领域，其核心目标是培育种间胚胎干细胞系，这些干细胞系有可能用于理解发育、分化、基因表达和基因组兼容性。它还将推动人类细胞疗法以及制药行业寻找新的药物靶点。如果这种方法要取得成功，需要回答许多生物学问题，此外，还必须考虑一些道德和伦理方面的问题。
