Schwarting Rainer K W
Experimental and Physiological Psychology, Philipps-University of Marburg, Gutenbergstr. 18, 35032 Marburg, Germany.
Behav Brain Res. 2009 Apr 12;199(1):76-88. doi: 10.1016/j.bbr.2008.07.004. Epub 2008 Jul 15.
Since the late eighties of the last century, when the so-called serial reaction time (SRT) task was first presented, analysis of sequential learning and performance has developed into a prosperous area of neurocognitive research in human subjects and non-human primates. In more recent years, rodent implementations of SRT tasks have become available, which will be summarized here and discussed with respect to their advantages, but also to their methodological and theoretical drawbacks. Then, a review of new neurobiological findings with such rodent tasks will be provided, that will be embedded into the existing theoretical framework, originally obtained from the work with primate species. Among others, this review will show that rodent SRT tasks allow actualizing and thus, studying many psychological features of human sequential tasks, for example, cognitive complexity of sequences. Since these rodent tasks can be used for a number of neuronal analyses, it is assumed that they will provide important insights for the neural mechanisms underlying such cognitive functions.
自上世纪八十年代末首次提出所谓的序列反应时（SRT）任务以来，对序列学习和表现的分析已发展成为人类受试者和非人类灵长类动物神经认知研究的一个繁荣领域。近年来，啮齿动物的SRT任务实现方式已经出现，本文将对此进行总结，并讨论其优点以及方法和理论上的缺点。然后，将提供对这些啮齿动物任务新的神经生物学发现的综述，这些发现将被纳入最初从灵长类动物研究中获得的现有理论框架。除此之外，本综述将表明，啮齿动物的SRT任务能够实现并因此研究人类序列任务的许多心理特征，例如序列的认知复杂性。由于这些啮齿动物任务可用于多种神经元分析，因此人们认为它们将为这些认知功能背后的神经机制提供重要见解。
