Srinivasan Sridhar, Schiffer Charles A
Division of Hematology/Oncology, Karmanos Cancer Institute, Wayne State University School of Medicine, HWCRB-4th Floor, 4100 John R, Detroit, MI 48201, USA.
Leuk Res. 2009 Apr;33(4):561-4. doi: 10.1016/j.leukres.2008.06.024. Epub 2008 Aug 3.
The occurrence of multiple myeloma and chronic lymphocytic leukemia in the same patient is very uncommon. The immunomodulatory agent lenalidomide has been shown to have high response rates in multiple myeloma and appears to be quite active in advanced CLL. We report two patients with concurrent CLL and MM who were both treated successfully with lenalidomide.
同一患者同时发生多发性骨髓瘤和慢性淋巴细胞白血病非常罕见。免疫调节剂来那度胺已被证明在多发性骨髓瘤中具有较高的缓解率，并且在晚期慢性淋巴细胞白血病中似乎也相当有效。我们报告了两名同时患有慢性淋巴细胞白血病和多发性骨髓瘤的患者，他们均接受来那度胺治疗并取得成功。
