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Idebenone, an agent improving cerebral metabolism, stimulates [14C]tyrosine uptake and [14C]catecholamine formation by cultured bovine adrenal chromaffin cells.

作者信息

Houchi H, Yoshizumi M, Minakuchi K, Azuma M, Morita K, Oka M

机构信息

Department of Pharmacology, Tokushima University School of Medicine, Japan.

出版信息

Biochem Pharmacol. 1991 Jul 25;42(4):951-4. doi: 10.1016/0006-2952(91)90059-e.

DOI:10.1016/0006-2952(91)90059-e
PMID:1867650
Abstract
摘要

相似文献

1
Idebenone, an agent improving cerebral metabolism, stimulates [14C]tyrosine uptake and [14C]catecholamine formation by cultured bovine adrenal chromaffin cells.艾地苯醌是一种改善脑代谢的药物，可刺激培养的牛肾上腺嗜铬细胞摄取[14C]酪氨酸并形成[14C]儿茶酚胺。
Biochem Pharmacol. 1991 Jul 25;42(4):951-4. doi: 10.1016/0006-2952(91)90059-e.
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Tetrodotoxin-insensitive Na+ channel activator palytoxin inhibits tyrosine uptake into cultured bovine adrenal chromaffin cells.河豚毒素不敏感的钠离子通道激活剂岩沙海葵毒素抑制酪氨酸摄入培养的牛肾上腺嗜铬细胞。
Mol Pharmacol. 1991 Jul;40(1):112-7.
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Idebenone inhibits catecholamine secretion through its blocking action on Ca2+ channels in cultured adrenal chromaffin cells.
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Increase in catecholamine release and 45Ca2+ uptake induced by GABA in cultured bovine adrenal chromaffin cells.GABA诱导培养的牛肾上腺嗜铬细胞中儿茶酚胺释放增加及45Ca2+摄取增加。
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ATP stimulated catecholamine secretion: response in perfused adrenal glands and a subpopulation of cultured chromaffin cells.
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Benzodiazepines facilitate the stimulatory action of gamma-aminobutyric acid (GABA) on basal and veratridine-evoked catecholamine release from cultured bovine adrenal chromaffin cells.苯二氮䓬类药物可促进γ-氨基丁酸（GABA）对培养的牛肾上腺嗜铬细胞基础和藜芦碱诱发的儿茶酚胺释放的刺激作用。
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Structural changes in chromaffin granules induced by divalent cations.
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Prolactin inhibits the activity of tyrosine hydroxylase in cultured bovine adrenal chromaffin cells in a dose-dependent manner.催乳素以剂量依赖的方式抑制培养的牛肾上腺嗜铬细胞中酪氨酸羟化酶的活性。
Brain Res. 1990 Sep 24;528(1):175-8. doi: 10.1016/0006-8993(90)90215-w.

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Improved antioxidant effect of idebenone-loaded polyethyl-2-cyanoacrylate nanocapsules tested on human fibroblasts.
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2
Idebenone. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in age-related cognitive disorders.艾地苯醌。对其药效学和药代动力学特性以及在年龄相关性认知障碍中的治疗应用的综述。
Drugs Aging. 1994 Aug;5(2):133-52. doi: 10.2165/00002512-199405020-00007.