Hosoi Takayuki
National Center for Geriatrics and Gerontology, Department of Advanced Medicine.
Clin Calcium. 2008 Aug;18(8):1084-8.
The diagnostic criteria of osteoporosis in Japan is comprised of low bone mineral density and presence of fragile fractures as risk factors for further fractures. In addition, the importance of differential diagnosis is emphasized in this criteria. The risk factors for fragile fractures independent from low mineral density and the presence of fragile fractures were included in the criteria for pharmacotherapy in the 2006 edition of guideline for prevention and treatment of osteoporosis. These factors include smoking, excessive alcohol, and familial history of femoral neck fractures. It would be a research question whether the removal of lifestyle-related risk factors are related to the reduction of fracture risk.
日本骨质疏松症的诊断标准包括低骨密度以及存在脆性骨折作为进一步骨折的危险因素。此外，该标准强调了鉴别诊断的重要性。2006年版骨质疏松症防治指南中，独立于低骨密度和脆性骨折存在的脆性骨折危险因素被纳入药物治疗标准。这些因素包括吸烟、过量饮酒以及股骨颈骨折家族史。去除与生活方式相关的危险因素是否与骨折风险降低相关将是一个研究问题。
