Gorai Itsuo
International University of Health and Welfare Atami Hospital, Department of Obstetrics and Gynecology.
Clin Calcium. 2008 Aug;18(8):1135-40.
A number of clinical risk factors that provide information on fracture risk over and above that given by BMD have been defined. WHO proposed FRAX (fracture risk assessment tool) in which the fracture probability could be calculated by the use of risk factors with or without BMD. The proposed independent risk factors are age, a prior fragility fracture, a parental history of hip fracture, smoking, use of systemic corticosteroids, excess alcohol intake, secondary osteoporosis, and rheumatoid arthritis. Management algorithms in postmenopausal women based on an health analysis have been proposed in several countries including UK, Sweden, Germany, USA and Canada.
已经确定了一些临床风险因素,这些因素能提供超出骨密度所提供信息的骨折风险信息。世界卫生组织提出了FRAX(骨折风险评估工具),通过使用有或无骨密度信息的风险因素来计算骨折概率。提出的独立风险因素包括年龄、既往脆性骨折史、髋部骨折家族史、吸烟、全身使用糖皮质激素、过量饮酒、继发性骨质疏松症和类风湿关节炎。包括英国、瑞典、德国、美国和加拿大在内的几个国家已经提出了基于健康分析的绝经后女性管理算法。