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Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp.
Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11116-21. doi: 10.1073/pnas.0804754105. Epub 2008 Aug 4.
2
Crystal structure of the catalytic alpha subunit of E. coli replicative DNA polymerase III.
Cell. 2006 Sep 8;126(5):881-92. doi: 10.1016/j.cell.2006.07.028.
3
Crystal structure of DNA polymerase III β sliding clamp from Mycobacterium tuberculosis.
Biochem Biophys Res Commun. 2011 Feb 11;405(2):272-7. doi: 10.1016/j.bbrc.2011.01.027. Epub 2011 Jan 8.
4
Structure of a sliding clamp on DNA.
Cell. 2008 Jan 11;132(1):43-54. doi: 10.1016/j.cell.2007.11.045.
6
Structure-based design of short peptide ligands binding onto the E. coli processivity ring.
J Med Chem. 2011 Jul 14;54(13):4627-37. doi: 10.1021/jm200311m. Epub 2011 Jun 9.
7
A dynamic polymerase exchange with Escherichia coli DNA polymerase IV replacing DNA polymerase III on the sliding clamp.
J Biol Chem. 2008 Apr 25;283(17):11260-9. doi: 10.1074/jbc.M709689200. Epub 2008 Feb 28.
8
Exchange between Escherichia coli polymerases II and III on a processivity clamp.
Nucleic Acids Res. 2016 Feb 29;44(4):1681-90. doi: 10.1093/nar/gkv1375. Epub 2015 Dec 10.
10
Solution structure of an "open" E. coli Pol III clamp loader sliding clamp complex.
J Struct Biol. 2016 Jun;194(3):272-81. doi: 10.1016/j.jsb.2016.03.003. Epub 2016 Mar 8.

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Systematic Determination of the Impact of Structural Edits on Peptide Accumulation into Mycobacteria.
ACS Chem Biol. 2025 Aug 15;20(8):1962-1979. doi: 10.1021/acschembio.5c00330. Epub 2025 Aug 1.
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Small molecules targeting the eubacterial β-sliding clamp discovered by combined and screening approaches.
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The bacterial DNA sliding clamp, β-clamp: structure, interactions, dynamics and drug discovery.
Cell Mol Life Sci. 2024 May 30;81(1):245. doi: 10.1007/s00018-024-05252-w.
7
Peptide-Based Covalent Inhibitors Bearing Mild Electrophiles to Target a Conserved His Residue of the Bacterial Sliding Clamp.
JACS Au. 2024 Jan 25;4(2):432-440. doi: 10.1021/jacsau.3c00572. eCollection 2024 Feb 26.
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Modulators of protein-protein interactions as antimicrobial agents.
RSC Chem Biol. 2021 Feb 3;2(2):387-409. doi: 10.1039/d0cb00205d. eCollection 2021 Apr 1.
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Genome copy number regulates inclusion expansion, septation, and infectious developmental form conversion in .
J Bacteriol. 2021 Mar 15;203(6). doi: 10.1128/JB.00630-20. Epub 2021 Jan 11.

本文引用的文献

1
Crystal structure of a DNA polymerase sliding clamp from a Gram-positive bacterium.
BMC Struct Biol. 2006 Jan 10;6:2. doi: 10.1186/1472-6807-6-2.
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Cellular DNA replicases: components and dynamics at the replication fork.
Annu Rev Biochem. 2005;74:283-315. doi: 10.1146/annurev.biochem.73.011303.073859.
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Conserved interactions in the Staphylococcus aureus DNA PolC chromosome replication machine.
J Biol Chem. 2005 May 6;280(18):18152-62. doi: 10.1074/jbc.M413595200. Epub 2005 Jan 12.
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Defining the position of the switches between replicative and bypass DNA polymerases.
EMBO J. 2004 Oct 27;23(21):4342-52. doi: 10.1038/sj.emboj.7600438. Epub 2004 Oct 7.
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Error-prone replication for better or worse.
Trends Microbiol. 2004 Jun;12(6):288-95. doi: 10.1016/j.tim.2004.04.004.
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A peptide switch regulates DNA polymerase processivity.
Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):14689-94. doi: 10.1073/pnas.2435454100. Epub 2003 Nov 20.
10

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