Santos Edward R G, Pinto Manuel R, Lonstein John E, Denis Francis, Garvey Timothy A, Perra Joseph H, Transfeldt Ensor E, Schwender James D
Department of Orthopaedics, University of Minnesota, Minneapolis, MN, USA.
J Spinal Disord Tech. 2008 Aug;21(6):418-21. doi: 10.1097/BSD.0b013e3181573cb3.
A study documenting major complications encountered in revision procedures for lumbar cage pseudoarthrosis.
To document the perioperative complications associated with revision surgery for threaded cylindrical cage pseudoarthrosis.
Pseudoarthrosis after cylindrical cage placement manifests as persistent or recurrent pain and disability after surgery. Revision strategies include isolated posterior stabilization and posterior bone grafting, versus circumferential revision where an attempt is made to remove the cages anteriorly, followed by posterior stabilization and fusion. Potential complications associated with these revision procedures have not been adequately documented in the past.
Forty-seven consecutive patients with the diagnosis of cylindrical cage pseudoarthrosis were surgically treated with either a circumferential revision (AP) or an isolated posterior instrumented fusion (P). All intraoperative and postoperative complications were documented. Radiographic interbody fusion rates and preoperative and postoperative visual analog scale (VAS) scores were documented.
Three of the AP patients, all with anterior cage placement at L5-S1, had iliac vein lacerations requiring repair. A fourth patient had a ureteral injury requiring subsequent nephrectomy. Three patients who underwent circumferential revision and 2 patients who had an isolated posterior procedure had postoperative complications, including 2 infections (1 AP and 1 P), 1 radiculopathy (P), and 2 patients with prolonged ileus (both AP). There was a statistically significant decrease in overall VAS scores postoperatively for the 2 groups using the paired t test (P<0.0001). There was no difference in either the preoperative (P=0.22) or 2-year postoperative (P=0.30) VAS scores between the AP and P groups [rank-sum (Mann-Whitney) t tests]. Interbody fusion was achieved in 79% (30 of 38 levels) in the AP group. The interbody fusion rate was 37% (8 of 22) for the P group.
Circumferential revision including cage removal, structural allograft placement, and posterior stabilization is associated with increased perioperative complications. Although an anterior approach showed increased interbody fusion rates, this technique did not lead to more superior clinical outcomes based on VAS scores. It remains to be shown by larger prospective studies if there is a true difference in outcome between these 2 groups that will justify the increased perioperative morbidity associated with attempted cage removal.
一项记录腰椎椎间融合器假关节翻修手术中主要并发症的研究。
记录螺纹柱状椎间融合器假关节翻修手术的围手术期并发症。
柱状椎间融合器置入后假关节形成表现为术后持续或反复的疼痛及功能障碍。翻修策略包括单纯后路稳定及后路植骨,以及环形翻修,即尝试从前路取出椎间融合器,随后进行后路稳定及融合。过去尚未充分记录这些翻修手术相关的潜在并发症。
47例诊断为柱状椎间融合器假关节的连续患者接受了环形翻修(前路)或单纯后路器械辅助融合(后路)手术治疗。记录所有术中及术后并发症。记录影像学椎间融合率以及术前和术后视觉模拟评分(VAS)。
3例接受前路手术的患者,均在L5-S1节段前路置入椎间融合器,发生髂静脉撕裂需修复。第4例患者发生输尿管损伤,随后需要肾切除术。3例接受环形翻修的患者和2例接受单纯后路手术的患者出现术后并发症,包括2例感染(1例前路和1例后路)、1例神经根病(后路)以及2例肠梗阻延长(均为前路)。使用配对t检验,两组术后总体VAS评分有统计学显著降低(P<0.0001)。前路组和后路组术前(P=0.22)或术后2年(P=0.30)VAS评分无差异[秩和(曼-惠特尼)t检验]。前路组椎间融合率为79%(38个节段中的30个)。后路组椎间融合率为37%(22个中的8个)。
包括取出椎间融合器、结构性同种异体骨植入及后路稳定的环形翻修与围手术期并发症增加相关。尽管前路手术显示椎间融合率增加,但基于VAS评分,该技术并未带来更优的临床结果。这两组之间在结局上是否存在真正差异,从而证明与尝试取出椎间融合器相关的围手术期发病率增加是合理的,仍有待更大规模的前瞻性研究来证实。