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非营利性生物医学公司。

Nonprofit biomedical companies.

作者信息

Conti R M, Meltzer D O, Ratain M J

机构信息

Department of Pediatrics, Section of Pediatric Hematology/Oncology, Center on Health and the Social Sciences, Program on Pharmaceutical Policy, Cancer Research Center, The University of Chicago, Chicago, Illinois, USA.

出版信息

Clin Pharmacol Ther. 2008 Aug;84(2):194-7. doi: 10.1038/clpt.2008.123.

DOI:10.1038/clpt.2008.123
PMID:18679181
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4591870/
Abstract

Nonprofit biomedical firms are an integrated market-based solution to improve incentives for investment in promising scientific areas that have high social value but minimal potential for profit. We briefly review the current market with an emphasis on the financing of innovative product development and propose ideas for new nonprofit companies centered on the health concerns of developed countries. We conclude with a suggestion that opportunities exist for nonprofit firms focused on cancer diagnostics, given the limitations of current financing incentives and ripe scientific opportunity.

摘要

非营利性生物医学公司是一种基于市场的综合解决方案,旨在改善对具有高社会价值但盈利潜力极小的有前景科学领域的投资激励。我们简要回顾当前市场,重点关注创新产品开发的融资情况,并针对以发达国家健康问题为核心的新型非营利性公司提出想法。鉴于当前融资激励的局限性和成熟的科学机遇,我们得出结论,专注于癌症诊断的非营利性公司存在机会。

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The critical need for alternative antiretroviral formulations, and obstacles to their development.对抗逆转录病毒替代制剂的迫切需求及其研发障碍。
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本文引用的文献

1
Market incentives and pharmaceutical innovation.市场激励与药物创新。
J Health Econ. 2008 Jul;27(4):1060-1077. doi: 10.1016/j.jhealeco.2008.01.002. Epub 2008 Feb 17.
2
Obstacles and opportunities in new drug development.新药研发中的障碍与机遇。
Clin Pharmacol Ther. 2008 Feb;83(2):210-2. doi: 10.1038/sj.clpt.6100462.
3
Economics of new oncology drug development.新型肿瘤药物研发的经济学
J Clin Oncol. 2007 Jan 10;25(2):209-16. doi: 10.1200/JCO.2006.09.0803.
4
Estimating the cost of new drug development: is it really 802 million dollars?估算新药研发成本:真的是8.02亿美元吗?
Health Aff (Millwood). 2006 Mar-Apr;25(2):420-8. doi: 10.1377/hlthaff.25.2.420.
5
Oxymoron no more: the potential of nonprofit drug companies to deliver on the promise of medicines for the developing world.不再矛盾:非营利性制药公司为发展中世界提供药品承诺的潜力。
Health Aff (Millwood). 2005 Jul-Aug;24(4):1057-63. doi: 10.1377/hlthaff.24.4.1057.