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Cancer-suppressive effect of RNase A and DNase I.

作者信息

Shklyaeva O A, Mironova N L, Malkova E M, Taranov O S, Ryabchikova E I, Zenkova M A, Vlasov V V

机构信息

Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences, pr. Akademika Lavrent'eva 8, Novosibirsk, 630090 Russia.

出版信息

Dokl Biochem Biophys. 2008 May-Jun;420:108-11. doi: 10.1134/s1607672908030034.

DOI:10.1134/s1607672908030034
PMID:18680903
Abstract
摘要

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MicroRNAs and the hallmarks of cancer.微小RNA与癌症的特征
Oncogene. 2006 Oct 9;25(46):6170-5. doi: 10.1038/sj.onc.1209911.
2
MicroRNA gene expression deregulation in human breast cancer.人类乳腺癌中MicroRNA基因表达失调
Cancer Res. 2005 Aug 15;65(16):7065-70. doi: 10.1158/0008-5472.CAN-05-1783.
3
Interactions of the cytotoxic RNase A dimers with the cytosolic ribonuclease inhibitor.细胞毒性核糖核酸酶A二聚体与胞质核糖核酸酶抑制剂的相互作用。
牛胰核糖核酸酶A：对其体内外抗肿瘤活性机制的深入研究
Pharmaceutics. 2022 May 30;14(6):1173. doi: 10.3390/pharmaceutics14061173.
4
Extracellular DNA Traps: Origin, Function and Implications for Anti-Cancer Therapies.细胞外DNA陷阱：起源、功能及对癌症治疗的意义
Front Oncol. 2022 Apr 27;12:869706. doi: 10.3389/fonc.2022.869706. eCollection 2022.
5
The systemic tumor response to RNase A treatment affects the expression of genes involved in maintaining cell malignancy.系统性肿瘤对核糖核酸酶A治疗的反应会影响参与维持细胞恶性程度的基因的表达。
Oncotarget. 2017 Aug 12;8(45):78796-78810. doi: 10.18632/oncotarget.20228. eCollection 2017 Oct 3.
6
Highly sensitive nuclease assays based on chemically modified DNA or RNA.基于化学修饰的DNA或RNA的高灵敏度核酸酶检测法。
Sensors (Basel). 2014 Jul 11;14(7):12437-50. doi: 10.3390/s140712437.
7
MicroRNA drop in the bloodstream and microRNA boost in the tumour caused by treatment with ribonuclease A leads to an attenuation of tumour malignancy.用核糖核酸酶 A 治疗导致血液中 microRNA 下降和肿瘤中 microRNA 增加，从而减弱肿瘤的恶性程度。
PLoS One. 2013 Dec 30;8(12):e83482. doi: 10.1371/journal.pone.0083482. eCollection 2013.
8
Cancer progression mediated by horizontal gene transfer in an in vivo model.体内模型中水平基因转移介导的癌症进展。
PLoS One. 2012;7(12):e52754. doi: 10.1371/journal.pone.0052754. Epub 2012 Dec 28.
FEBS Lett. 2005 May 9;579(12):2663-8. doi: 10.1016/j.febslet.2005.03.087. Epub 2005 Apr 9.
4
Antitumor activity and other biological actions of oligomers of ribonuclease A.
J Biol Chem. 2003 Jun 27;278(26):23817-22. doi: 10.1074/jbc.M302711200. Epub 2003 Apr 14.
5
Secretory ribonucleases are internalized by a dynamin-independent endocytic pathway.分泌型核糖核酸酶通过一种不依赖发动蛋白的内吞途径被内化。
J Cell Sci. 2003 Jan 15;116(Pt 2):313-24. doi: 10.1242/jcs.00214.
6
Increased exposure of anionic phospholipids on the surface of tumor blood vessels.肿瘤血管表面阴离子磷脂暴露增加。
Cancer Res. 2002 Nov 1;62(21):6132-40.
7
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8
Potent and specific antitumor effects of an anti-CD22-targeted cytotoxic ribonuclease: potential for the treatment of non-Hodgkin lymphoma.一种抗CD22靶向细胞毒性核糖核酸酶的强效和特异性抗肿瘤作用：治疗非霍奇金淋巴瘤的潜力
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Horizontal transfer of DNA by the uptake of apoptotic bodies.
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