Fialkow Michael F, Newton Katherine M, Weiss Noel S
Department of Obstetrics and Gynecology, University of Washington School of Medicine, Box 356460, Seattle, WA, 98195, USA.
Int Urogynecol J Pelvic Floor Dysfunct. 2008 Nov;19(11):1483-7. doi: 10.1007/s00192-008-0678-8. Epub 2008 Aug 6.
We conducted this study to estimate the rate of, and identify risk factors for, recurrent pelvic organ prolapse (POP) following primary surgical repair. The study consisted of a retrospective cohort study of 142 women who underwent primary surgical management of POP in 1993 and were followed up to 10 years. Prolapse severity was graded using an established classification system of clinical descriptors. Hazard ratios (HR) for recurrent POP were determined using Cox regression. 36 recurrent cases were identified (recurrence rate: 3.7 per 100 woman-years). A cystocele was the most frequent element of primary (87%) and recurrent (72%) prolapse. No predictors of the likelihood of recurrence were identified, though recurrence was somewhat more common among women with a history of two or fewer vaginal deliveries vs three or more (HR = 1.6; 95% confidence interval = 0.81-3.3). Recurrent POP following surgical management is common. Our ability to predict recurrence is limited.
我们开展这项研究以评估初次手术修复后盆腔器官脱垂（POP）复发的发生率并确定其风险因素。该研究为一项回顾性队列研究，纳入了1993年接受POP初次手术治疗且随访长达10年的142名女性。采用既定的临床描述符分类系统对脱垂严重程度进行分级。使用Cox回归确定POP复发的风险比（HR）。共识别出36例复发病例（复发率：每100女性年3.7例）。膀胱膨出是初次脱垂（87%）和复发脱垂（72%）最常见的组成部分。未识别出复发可能性的预测因素，不过有两次或更少阴道分娩史的女性复发情况比有三次或更多阴道分娩史的女性更为常见（HR = 1.6；95%置信区间 = 0.81 - 3.3）。手术治疗后POP复发很常见。我们预测复发的能力有限。
