Leonard Jennifer A
Genetics Program, Smithsonian Institution, 3001 Connecticut Avenue NW, Washington, DC 20008-0551, USA.
Mol Ecol. 2008 Oct;17(19):4186-96. doi: 10.1111/j.1365-294X.2008.03891.x.
Ancient DNA analyses of historical, archaeological and paleontological remains can contribute important information for the conservation of populations and species that cannot be obtained any other way. In addition to ancient DNA analyses involving a single or few individuals, population level studies are now possible. Biases inherent in estimating population parameters and history from modern genetic diversity are exaggerated when populations are small or have been heavily impacted by recent events, as is common for many endangered species. Going directly back in time to study past populations removes many of the assumptions that undermine conclusions based only on recent populations. Accurate characterization of historic population size, levels of gene flow and relationships with other populations are fundamental to developing appropriate conservation and management plans. The incorporation of ancient DNA into conservation genetics holds a lot of potential, if it is employed responsibly.
对历史、考古和古生物学遗迹进行古DNA分析可为种群和物种的保护提供重要信息,而这些信息无法通过其他方式获得。除了涉及单个或少数个体的古DNA分析外,现在还可以进行种群水平的研究。当种群规模较小或受到近期事件的严重影响时(许多濒危物种都普遍如此),从现代遗传多样性估计种群参数和历史时固有的偏差会被放大。直接回溯过去研究过去的种群消除了许多仅基于近期种群得出结论时所依据的假设。准确描述历史种群规模、基因流动水平以及与其他种群的关系对于制定适当的保护和管理计划至关重要。如果负责任地使用,将古DNA纳入保护遗传学具有很大潜力。