Coates Thomas J, Richter Linda, Caceres Carlos
UCLA Program in Global Health, Division of Infectious Diseases, University of California, Los Angeles, CA, USA.
Lancet. 2008 Aug 23;372(9639):669-84. doi: 10.1016/S0140-6736(08)60886-7. Epub 2008 Aug 5.
This paper makes five key points. First is that the aggregate effect of radical and sustained behavioural changes in a sufficient number of individuals potentially at risk is needed for successful reductions in HIV transmission. Second, combination prevention is essential since HIV prevention is neither simple nor simplistic. Reductions in HIV transmission need widespread and sustained efforts, and a mix of communication channels to disseminate messages to motivate people to engage in a range of options to reduce risk. Third, prevention programmes can do better. The effect of behavioural strategies could be increased by aiming for many goals (eg, delay in onset of first intercourse, reduction in number of sexual partners, increases in condom use, etc) that are achieved by use of multilevel approaches (eg, couples, families, social and sexual networks, institutions, and entire communities) with populations both uninfected and infected with HIV. Fourth, prevention science can do better. Interventions derived from behavioural science have a role in overall HIV-prevention efforts, but they are insufficient when used by themselves to produce substantial and lasting reductions in HIV transmission between individuals or in entire communities. Fifth, we need to get the simple things right. The fundamentals of HIV prevention need to be agreed upon, funded, implemented, measured, and achieved. That, presently, is not the case.
本文提出了五个关键点。首先,要成功减少艾滋病毒传播,需要足够数量的潜在风险个体发生彻底且持续的行为改变,产生总体效果。其次,联合预防至关重要,因为艾滋病毒预防既不简单也不单一。减少艾滋病毒传播需要广泛且持续的努力,以及多种传播渠道来传递信息,激励人们采取一系列降低风险的措施。第三,预防项目可以做得更好。通过采用多层次方法(如夫妻、家庭、社会和性网络、机构以及整个社区)针对未感染和已感染艾滋病毒的人群实现多个目标(如推迟首次性行为开始时间、减少性伴侣数量、增加避孕套使用等),行为策略的效果可以得到增强。第四,预防科学可以做得更好。源自行为科学的干预措施在整体艾滋病毒预防工作中发挥着作用,但仅靠它们自身不足以在个体之间或整个社区大幅且持久地减少艾滋病毒传播。第五,我们需要把简单的事情做好。艾滋病毒预防的基本要素需要达成共识、获得资金、加以实施、进行衡量并实现。但目前情况并非如此。