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非洲农村地区的艾滋病:HIV-1预防范例

AIDS in rural Africa: a paradigm for HIV-1 prevention.

作者信息

Hudson C P

出版信息

Int J STD AIDS. 1996 Jul;7(4):236-43. doi: 10.1258/0956462961917906.

DOI:10.1258/0956462961917906
PMID:8876353
Abstract

Networks of concurrent sexual partnerships may be the primary cause of epidemic spread of HIV-1 in parts of sub-Saharan Africa. This pattern of sexual behaviour increases the likelihood that individuals experiencing primary HIV-1 infection transmit the virus to other persons. Networks of concurrent partnerships are likely to be important in both the early ('epidemic') and late ('endemic') phases of HIV-1 transmission. Interventions should aim to break the sexual networks, whatever the stage of the epidemic. However, prevention of transmission in the endemic phase also requires a greater awareness of early clinical manifestations of HIV-1 infection in the general population. Such awareness, coupled with the availability of condoms and access to HIV-1 testing facilities, may reduce transmission in discordant couples.

摘要

同时存在性伴侣关系网络可能是撒哈拉以南非洲部分地区HIV-1流行传播的主要原因。这种性行为模式增加了初次感染HIV-1的个体将病毒传播给其他人的可能性。同时性伴侣关系网络在HIV-1传播的早期(“流行期”)和晚期(“地方病期”)可能都很重要。无论疫情处于哪个阶段,干预措施都应旨在打破性网络。然而,在地方病期预防传播还需要提高普通人群对HIV-1感染早期临床表现的认识。这种认识,再加上避孕套的可获得性以及获得HIV-1检测设施的机会,可能会减少不一致伴侣之间的传播。

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