Keller Martha, Moliner José L, Vásquez Grettys, Cruz Danilo, Bello Orestes, Costidis Alex M, Rommel Sentiel A, Mays Maron B Calderwood, Gearhart Scott
Marine Mammal Pathobiology Laboratory, 3700 54th Ave. South, St. Petersburg, Florida 33711, USA.
J Wildl Dis. 2008 Jul;44(3):707-11. doi: 10.7589/0090-3558-44.3.707.
Two West Indian manatees (Trichechus manatus spp.) were reported with severe emaciation. One animal was a Florida manatee from the Everglades; the other was an Antillean manatee from Cuba. On necropsy, both animals had nephrolithiasis, pyelonephritis, and moderate to severe renomegaly. Histopathology revealed multifocal to diffuse pyelonephritis, interstitial nephritis, and nephrocalcinosis. The stones were analyzed and consisted primarily of calcium carbonate. Serum chemistry values for the Florida animal revealed no renal abnormalities. The mechanism of calculus formation remains unclear in manatees. In horses, another hindgut fermenter, the most common urolith is also calcium carbonate. Urinalyses performed on manatees are very similar to those of horses (i.e., alkaline urine, low specific gravity, and calcium carbonate crystals). Formation of uroliths in manatees may have a pathogenesis similar to equine urolithiasis.
据报道，两只西印度海牛（Trichechus manatus spp.）出现严重消瘦。其中一只动物是来自大沼泽地的佛罗里达海牛；另一只来自古巴的安的列斯海牛。尸检时，两只动物均患有肾结石、肾盂肾炎和中度至重度肾肿大。组织病理学显示多灶性至弥漫性肾盂肾炎、间质性肾炎和肾钙质沉着症。对结石进行分析，发现主要成分是碳酸钙。佛罗里达海牛的血清化学值未显示出肾脏异常。海牛结石形成的机制仍不清楚。在另一种后肠发酵动物马中，最常见的尿路结石也是碳酸钙。对海牛进行的尿液分析与马的尿液分析非常相似（即碱性尿液、低比重和碳酸钙晶体）。海牛尿路结石的形成可能具有与马尿路结石病相似的发病机制。
