Demoly P, Didier A, Mathelier-Fusade P, Drouet M, David M, Bonnelye G, Blic J de, Klossek J M
Unité d'Exploration des Allergies, INSERM U657 Hôpital Arnaud de Villeneuve, Montpellier, France.
Allergy. 2008 Aug;63(8):1008-14. doi: 10.1111/j.1398-9995.2008.01666.x.
Specific immunotherapy (SIT) is the only aetiological treatment used in allergic rhinitis (AR). A telephone survey of patients and physicians in France was carried out to understand better the real and perceived advantages and inconveniences of this therapeutic approach.
A cohort of 453 individuals with AR was selected using the Score For Allergic Rhinitis questionnaire. The survey evaluated the level of understanding of allergic rhinitis and its management, including both pharmacotherapy and SIT. A parallel survey was conducted with 400 general practitioners, allergists and nonallergist specialists.
Approximately 50% of patients had heard about SIT as a therapeutic option. Of these, 56% had a positive view of SIT and 14% a negative image. A majority of patients and physicians with a positive opinion associated SIT with improved well-being and quality of life, while those with a negative opinion considered it to be a long and inconvenient treatment, with uncertain results. Over 50% of patients who had been offered SIT had accepted it and approximately 60% of these were satisfied with it. The future availability of SIT as sublingual tablets was perceived positively by both patients and physicians.
Many patients with AR are unaware of their pathology and few seek help from health professionals. When patients take medication, they are generally satisfied with their treatment, even if it is only symptomatic. Patients and physicians see the notion of definitive recovery as the main benefit of SIT, whereas the main disadvantage is the duration of treatment.
特异性免疫疗法(SIT)是变应性鼻炎(AR)唯一的病因治疗方法。在法国对患者和医生进行了一项电话调查,以更好地了解这种治疗方法的实际和感知到的优点及不便之处。
使用变应性鼻炎评分问卷选择了453名AR患者队列。该调查评估了对变应性鼻炎及其管理的理解程度,包括药物治疗和SIT。对400名全科医生、过敏症专科医生和非过敏症专科医生进行了一项平行调查。
约50%的患者听说过SIT作为一种治疗选择。其中,56%对SIT持积极看法,14%持负面看法。大多数持积极看法的患者和医生将SIT与幸福感和生活质量的改善联系起来,而持负面看法的人则认为这是一种漫长且不便的治疗方法,结果不确定。超过50%被提供SIT的患者接受了它,其中约60%对其满意。患者和医生对SIT作为舌下片剂的未来可用性都持积极看法。
许多AR患者不了解自己的病情,很少向卫生专业人员寻求帮助。当患者服药时,他们通常对治疗感到满意,即使只是对症治疗。患者和医生将最终康复的概念视为SIT的主要益处,而主要缺点是治疗持续时间。