Simonsen Mette K, Hundrup Yrsa A, Grønbaek Morten, Heitmann Berit L
Research Unit for Dietary Studies, Institute of Preventive Medicine, Centre for Health and Society, Copenhagen, Denmark.
BMC Womens Health. 2008 Aug 8;8:13. doi: 10.1186/1472-6874-8-13.
Obesity and self-rated health (SRH) are strong predictors of morbidity and mortality but their interrelation is sparsely studied. The aim of this study was to analyse the association between weight changes and changes in SRH among women. We also examined if poor SRH at baseline was associated with later weight gain.
The Danish Nurse Cohort Study is a prospective population study (1993-1999) and comprises 13,684 female nurses aged 44 to 69 years. Logistic regression analyses were used to examine the association between weight changes and changes in SRH.
Women who gained weight during the study period had higher odds of reporting poorer self-rated health (Odds Ratio (OR): 1.18, 95% CI: 1.04-1.35). Weight loss among overweight women, did not result in an increase in self-rated health ratings, in fully adjusted analyses (0.96 (95% CI: 0.76-1.23). Poor self-rated health combined with normal weight at first examination was associated with higher odds of later weight gain (OR: 1.29, 95% CI: 1.10-1.51).
Weight changes may result in lower SRH. Further, poor self-rated health at baseline seems to predict an increase in weight, among women without any longstanding chronic diseases. Future obesity prevention may focus on normal weight individuals with poor SRH.
肥胖和自评健康状况(SRH)是发病率和死亡率的重要预测指标,但它们之间的相互关系鲜有研究。本研究的目的是分析女性体重变化与SRH变化之间的关联。我们还研究了基线时SRH较差是否与后期体重增加有关。
丹麦护士队列研究是一项前瞻性人群研究(1993 - 1999年),包括13684名年龄在44至69岁之间的女性护士。采用逻辑回归分析来研究体重变化与SRH变化之间的关联。
在研究期间体重增加的女性报告自评健康状况较差的几率更高(优势比(OR):1.18,95%置信区间:1.04 - 1.35)。在完全调整分析中,超重女性体重减轻并未导致自评健康评分增加(0.96(95%置信区间:0.76 - 1.23))。首次检查时自评健康状况较差且体重正常与后期体重增加的几率较高有关(OR:1.29,95%置信区间:1.10 - 1.51)。
体重变化可能导致SRH降低。此外,在没有任何长期慢性病的女性中,基线时自评健康状况较差似乎预示着体重增加。未来的肥胖预防可能侧重于SRH较差的正常体重个体。