Suppr超能文献

肥胖程度增加对血管外科手术预后的影响。

The effects of increasing obesity on outcomes of vascular surgery.

作者信息

Khandanpour Nader, Armon Matthew P, Foxall Rob, Meyer Felicity J

机构信息

Vascular Surgery Department, Norfolk and Norwich Vascular Unit, Norfolk and Norwich University Hospital, Norwich, UK.

出版信息

Ann Vasc Surg. 2009 May-Jun;23(3):310-6. doi: 10.1016/j.avsg.2008.05.012. Epub 2008 Aug 6.

Abstract

The aim of this study was to determine whether vascular patients are becoming progressively more obese and whether morbid obesity affects outcomes from vascular surgery. Data for the index vascular procedures of infrainguinal bypass, carotid endarterectomy, and abdominal aortic aneurysm (AAA) repair were collected in a computer database for 1996-2006. Body mass index (BMI) was stratified into <18.5 kg/m2 as underweight, >35 kg/m2 as morbidly obese, and other as control (18.5 < BMI < 35). The data were analyzed with respect to operation duration, length of stay, complication rates, and mortality rates. Results were adjusted for potential confounding variables, including mode of admission, diabetes, cardiac history, renal function, and smoking. A total of 1,317 patients were reviewed, and 1,105 cases were deemed suitable for analysis. The incidence of morbid obesity increased in a linear manner from 1.3% to 9% over the 10-year period. The operation duration was longer for morbidly obese subjects compared with normals. This was only statistically significant for AAA repair category, with a mean operating time of 158.4 +/- 65.5 min for patients with BMI <35 kg/m2 vs. 189.8 +/- 92.2 min for morbidly obese patients (p < 0.014). Infection rates were consistently higher in the morbidly obese group; however, this reached a statistically significant rate among AAA repair cases (43.5% [n = 16] vs. 34.8% [n = 159], p < 0.004). There were no significant differences in other complications, graft failure, length of stay, or mortality. Vascular patients are becoming progressively more obese. Procedures performed on morbidly obese subjects take longer, and these patients have higher rates of infectious complications. This is mainly attributable to AAA. This did not translate into poorer final outcomes in this study, although significant differences might emerge from a larger sample.

摘要

本研究的目的是确定血管疾病患者是否正变得越来越肥胖,以及病态肥胖是否会影响血管手术的预后。1996年至2006年期间,腹股沟下旁路移植术、颈动脉内膜切除术和腹主动脉瘤(AAA)修复术等主要血管手术的数据被收集到一个计算机数据库中。体重指数(BMI)被分为体重过轻(<18.5 kg/m2)、病态肥胖(>35 kg/m2)以及其他作为对照组(18.5<BMI<35)。对手术时间、住院时间、并发症发生率和死亡率等数据进行了分析。对包括入院方式、糖尿病、心脏病史、肾功能和吸烟等潜在混杂变量进行了结果校正。共审查了1317例患者,其中1105例被认为适合分析。在这10年期间,病态肥胖的发生率以线性方式从1.3%上升至9%。与正常体重者相比,病态肥胖者的手术时间更长。这仅在AAA修复类别中具有统计学意义,BMI<35 kg/m2的患者平均手术时间为158.4±65.5分钟,而病态肥胖患者为189.8±92.2分钟(p<0.014)。病态肥胖组的感染率一直较高;然而,这在AAA修复病例中达到了统计学显著水平(43.5%[n=16]对34.8%[n=159],p<0.004)。在其他并发症、移植物失败、住院时间或死亡率方面没有显著差异。血管疾病患者正变得越来越肥胖。对病态肥胖患者进行的手术时间更长,且这些患者的感染并发症发生率更高。这主要归因于AAA。在本研究中,这并未转化为更差的最终预后,尽管更大样本可能会出现显著差异。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验