Pont Stephen J, Carpenter L Rand, Griffin Marie R, Jones Timothy F, Schaffner William, Dudley Judith A, Arbogast Patrick G, Cooper William O
Department of Pediatrics, Vanderbilt University, Nashville, TN.
J Pediatr. 2008 Dec;153(6):777-82. doi: 10.1016/j.jpeds.2008.06.037. Epub 2008 Aug 9.
To determine current diarrhea-associated healthcare usage rates and associated sociodemographic factors. These data can be used to determine the impact of the rotavirus vaccine.
Using discharge diagnosis codes, we determined diarrhea-associated visit rates for children aged 0 to 18 years enrolled in Tennessee Medicaid, 1995-2004. Poisson regression compared data across time and within strata. The winter residual excess method estimated the rotavirus burden.
Analyzing approximately 500 000 person-years annually, outpatient and hospitalization rates remained stable from 1995 to 2004; emergency department (ED) rates approximately doubled, incidence rate ratio (IRR): 1.92 (1.81-2.04). White children used healthcare at greater rates than black children: outpatient IRR 1.90: (1.85-1.95), ED IRR: 1.69 (1.64-1.74), and inpatient IRR: 1.82 (1.73-1.92); and rural children greater than urban: outpatient IRR 1.66 (1.62-1.70), ED IRR 1.14 (1.11-1.17), inpatient IRR 1.88 (1.80-1.97). Children aged 0 to 35 months experienced 1627 outpatient and 792 ED visits, and 148 hospitalizations per 10 000 child-years; rotavirus may have affected up to 40% of these hospitalizations.
Diarrhea-associated ED visit rates nearly doubled from 1995 to 2004. Future studies could explore factors resulting in increased healthcare usage by white children and those living in rural areas and document the rotavirus vaccine's impact after its release.
确定当前腹泻相关医疗保健使用率及相关社会人口学因素。这些数据可用于确定轮状病毒疫苗的影响。
利用出院诊断编码,我们确定了1995 - 2004年田纳西医疗补助计划中0至18岁儿童的腹泻相关就诊率。采用泊松回归对不同时间和分层的数据进行比较。冬季剩余超额法估算轮状病毒负担。
每年分析约50万人年的数据,1995年至2004年门诊和住院率保持稳定;急诊科就诊率约翻倍,发病率比(IRR):1.92(1.81 - 2.04)。白人儿童的医疗保健使用率高于黑人儿童:门诊IRR为1.90(1.85 - 1.95),急诊科IRR为1.69(1.64 - 1.74),住院IRR为1.82(1.73 - 1.92);农村儿童高于城市儿童:门诊IRR为1.66(1.62 - 1.70),急诊科IRR为1.14(1.11 - 1.17),住院IRR为1.88(1.80 - 1.97)。0至35个月大的儿童每10000儿童年有1627次门诊就诊、792次急诊科就诊和148次住院;轮状病毒可能影响了其中高达40%的住院病例。
1995年至2004年腹泻相关的急诊科就诊率几乎翻倍。未来的研究可以探索导致白人儿童和农村地区儿童医疗保健使用增加的因素,并记录轮状病毒疫苗上市后的影响。