Wosje Karen S, Khoury Philip R, Claytor Randal P, Copeland Kristen A, Kalkwarf Heidi J, Daniels Stephen R
Division of General and Community Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229-3039, USA.
J Pediatr. 2009 Jan;154(1):79-85.e2. doi: 10.1016/j.jpeds.2008.06.031. Epub 2008 Aug 9.
To examine the relation between baseline fat mass and gain in bone area and bone mass in preschoolers studied prospectively for 4 years, with a focus on the role of physical activity and TV viewing.
Children were part of a longitudinal study in which measures of fat, lean and bone mass, height, weight, activity, and diet were taken every 4 months from ages 3 to 7 years. Activity was measured by accelerometer and TV viewing by parent checklist. We included 214 children with total body dual energy x-ray absorptiometry (Hologic 4500A) scans at ages 3.5 and 7 years.
Higher baseline fat mass was associated with smaller increases in bone area and bone mass over the next 3.5 years (P < .001). More TV viewing was related to smaller gains in bone area and bone mass accounting for race, sex, and height. Activity by accelerometer was not associated with bone gains.
Adiposity and TV viewing are related to less bone accrual in preschoolers.
前瞻性研究4年，以探讨学龄前儿童基线脂肪量与骨面积和骨量增加之间的关系，重点关注身体活动和看电视的作用。
儿童参与一项纵向研究，从3岁至7岁每4个月测量一次脂肪、瘦体重、骨量、身高、体重、活动量和饮食情况。活动量通过加速度计测量，看电视情况通过家长填写的清单记录。我们纳入了214名在3.5岁和7岁时接受全身双能X线吸收仪（Hologic 4500A）扫描的儿童。
较高的基线脂肪量与接下来3.5年骨面积和骨量的较小增加相关（P < .001）。考虑到种族、性别和身高因素，看电视时间越长，骨面积和骨量的增加越小。通过加速度计测量的活动量与骨量增加无关。
肥胖和看电视与学龄前儿童骨量积累较少有关。
