Lolom Isabelle, Deblangy Claude, Capelle Annick, Guerinot Wafaa, Bouvet Elisabeth, Barry Beatrix, Goyau Katel, L'heriteau François, Bonnal Christine, Lucet Jean-Christophe
Unité d'hygiène et de lutte contre l'infection nosocomiale, Hôpital Bichat-Claude Bernard, Assistance publique-Hôpitaux de Paris, et Faculté Denis Diderot Paris VI, F-75000 Paris, France.
Presse Med. 2009 Jan;38(1):34-42. doi: 10.1016/j.lpm.2008.03.017. Epub 2008 Aug 9.
Although peripheral venous catheter (PVC) placement is one of the most common invasive procedures used in hospitals, data about the infectious risk associated with it are sparse. Nurses and physicians often underestimate this risk. We describe here a 10-year continuous quality improvement program in a large university hospital.
The prevention program included: 1/ an observational audit of practices of PVC insertion and maintenance (1996), 2/ two studies of incidence and risk factors for PVC-related infection (1996 and 1999), 3/ 8 annual (1996 to 2006) cross-sectional studies that collected information about duration of PVC placement and other process indicators, 4/ surveillance of nosocomial bacteremia from 2002 through 2006, and 5/ continued education sessions for healthcare workers, based on local surveillance data.
Rates of colonization and infection (0.7 cases of bacteremia/1000 PVC days) were similar to data from other studies. PVC that remained in place for more than three days was associated with a higher risk of catheter-related bacteremia in both incidence studies. The annual prevalence studies showed that 15 to 20% of PVCs remained in place for more than three days from 1996 through 2002, but this rate decreased thereafter; it was 6.7% in 2005 and 10.7% in 2006. Practices audits indicated room for improvement in prevention measures. The absolute number of PVC-related bacteremia decreased by more than 50% from 2002 (n=23) to 2006 (n=10).
This prolonged multifaceted program, including practice audits, continued medical education and monitoring of PVC-related infection, has led to a substantial decrease over time in the infectious risk related to PVC placement.
尽管外周静脉导管(PVC)置入是医院中最常用的侵入性操作之一,但与之相关的感染风险数据却很稀少。护士和医生常常低估这种风险。我们在此描述一所大型大学医院开展的一项为期10年的持续质量改进项目。
预防项目包括:1/对PVC插入和维护操作的观察性审核(1996年),2/两项关于PVC相关感染的发生率及危险因素的研究(1996年和1999年),3/8项年度(1996年至2006年)横断面研究,收集有关PVC留置时间及其他过程指标的信息,4/2002年至2006年对医院获得性菌血症的监测,以及5/根据当地监测数据为医护人员开展继续教育课程。
定植和感染率(0.7例菌血症/1000个PVC留置日)与其他研究的数据相似。在两项发生率研究中,留置超过三天的PVC与导管相关菌血症的较高风险相关。年度患病率研究表明,1996年至2002年期间,15%至20%的PVC留置超过三天,但此后该比例下降;2005年为6.7%,2006年为10.7%。操作审核表明预防措施有改进空间。与PVC相关的菌血症绝对数从2002年(n = 23)到2006年(n = 10)减少了50%以上。
这个长期的多方面项目,包括操作审核、持续医学教育以及对PVC相关感染的监测,随着时间推移已使与PVC置入相关的感染风险大幅降低。