Shoaib Shaheen, Tauheed Shoaib, Hafeez Amtul
Dow University of Health Sciences, Karachi, Pakistan.
J Ayub Med Coll Abbottabad. 2007 Oct-Dec;19(4):40-1.
Cutaneous Leishmaniasis (CL) has been an endemic parasitic infection in certain areas of Pakistan. New outbreaks have occurred in many areas not identified previously especially in the province of Sindh. The object of this study was to see the prevalence of CL as a childhood disease.
It was a cross sectional study in which 400 cases coming to various skin disease clinics were included for confirmation of CL by microscopy, culture and PCR.
Out of 400 cases, 185 cases of ages from 1-14 years were diagnosed clinically and confirmed by Lab. Tests for CL. Both dry and wet types of lesions were observed that indicated presence of more than one strain of the parasite.
Cutaneous Leishmaniasis was found to be significantly prevalent in children. The strains were found to be L. tropica and L. major as was indicated by the nature of lesions and confirmed by PCR.
皮肤利什曼病（CL）在巴基斯坦的某些地区一直是一种地方性寄生虫感染。新的疫情在许多以前未被确认的地区爆发，特别是在信德省。本研究的目的是了解CL作为一种儿童疾病的患病率。
这是一项横断面研究，纳入了400例到各种皮肤病诊所就诊的病例，通过显微镜检查、培养和聚合酶链反应（PCR）来确诊CL。
在400例病例中，有185例年龄在1至14岁之间的病例经临床诊断并通过实验室检测确诊为CL。观察到了干性和湿性两种病变类型，这表明存在不止一种寄生虫菌株。
发现皮肤利什曼病在儿童中显著流行。根据病变性质并经PCR确认，发现菌株为热带利什曼原虫和硕大利什曼原虫。
