Zafar Azra, Shahid Syed Khurram, Siddiqui Maimoona, Khan Farrukh Shohab
Department of Neurology, Liaquat National Hospital, Karachi.
J Ayub Med Coll Abbottabad. 2007 Oct-Dec;19(4):64-7.
Diabetes mellitus is a well-recognized risk factor for ischaemic stroke. Stroke in diabetic patients is different from stroke in non-diabetics from several perspectives. There is no local study on this topic. This is the first study from Pakistan, in which pattern of stroke in diabetics have been described and compared with non-diabetics. The object of this study was to compare pattern of stroke in diabetic subjects with non-diabetics.
This is a prospective comparative cross sectional study, carried out at Liaquat national hospital, Karachi, neurology department from October to March 2006. Fifty patients were enrolled in diabetic group and 50 in non-diabetic. Clinical features, risk factors and stroke patterns were identified.
Mean age was 59.5 (+/- 11.82) in diabetics and 60.4 (+/- 14.8) in non diabetics. There was slight preponderance of male patients in non diabetic group. Out of 50 diabetic patients, 44 (88.0%) had ischaemic stroke and 6 (12.0%) had intracerebral haemorrhage. In non-diabetics, 29 (58.0%) had ischaemic stroke while 21 (42.0%) had intracerebral haemorrhage. On further analysis of ischaemic stroke, cortical infarcts (CI) was found in 22, sub cortical infarcts (SCI) in 14, brainstem in 5 and cerebellar in 2 diabetic patients. CI was also the commonest subtype of ischaemic stroke in nondiabetics.
Patterns of stroke in diabetics are different from non-diabetics. Ischaemic stroke is more prevalent than hemorrhagic strokein diabetics. Sub cortical infarcts are more common in diabetics than non diabetics (p = 0.04).
糖尿病是公认的缺血性卒中危险因素。糖尿病患者的卒中在多个方面与非糖尿病患者的卒中不同。目前尚无关于该主题的本地研究。这是来自巴基斯坦的第一项研究，其中描述了糖尿病患者的卒中模式并与非糖尿病患者进行了比较。本研究的目的是比较糖尿病患者与非糖尿病患者的卒中模式。
这是一项前瞻性比较横断面研究，于2006年10月至3月在卡拉奇利亚卡特国家医院神经科进行。糖尿病组纳入50例患者，非糖尿病组纳入50例患者。确定临床特征、危险因素和卒中模式。
糖尿病患者的平均年龄为59.5（±11.82）岁，非糖尿病患者为60.4（±14.8）岁。非糖尿病组男性患者略多。50例糖尿病患者中，44例（88.0%）发生缺血性卒中，6例（12.0%）发生脑出血。在非糖尿病患者中，29例（58.0%）发生缺血性卒中，21例（42.0%）发生脑出血。对缺血性卒中进行进一步分析发现，22例糖尿病患者发生皮质梗死（CI），14例发生皮质下梗死（SCI），5例发生脑干梗死，2例发生小脑梗死。CI也是非糖尿病患者缺血性卒中最常见的亚型。
糖尿病患者的卒中模式与非糖尿病患者不同。糖尿病患者中缺血性卒中比出血性卒中更常见。糖尿病患者皮质下梗死比非糖尿病患者更常见（p = 0.04）。
