Mahboob Atiya, Haroon Tahir Saeed, Iqbal Zafar, Saleemi Munir Akhtar, Munir Asma
Department of Dermatology, Shaikh Zayed Federal PGMI Lahore, Pakistan.
J Ayub Med Coll Abbottabad. 2007 Oct-Dec;19(4):68-70.
To determine the prevalence of hepatitis B surface antigen carrier state in patients with lichen planus.
A quasi experimental cross sectional study was done at Department of Dermatology, Shaikh Zayed Federal Postgraduate Medical Institute, Lahore, Pakistan, from April 2003 to March 2005. Two hundred clinically diagnosed cases of LP and equal number of patients with other dermatoses not reportedly associated with hepatitis B virus (HBV) infection (control group) were collected from Skin Out Patient Department. They were screened for hepatitis B surface antigen (HBsAg) by Enzyme Linked Immunosorbent Assay (ELISA). Statistical analysis was done by using SPSS package version 11.
Out of 200 patients of each group, three patients with LP and seven patients from control group were positive for HBsAg. The test of significance for proportions revealed that there was no significant difference (p > 0.1) between two groups.
No association between HBsAg carrier state and LP was found in our study.
确定扁平苔藓患者中乙肝表面抗原携带者状态的患病率。
2003年4月至2005年3月在巴基斯坦拉合尔谢赫·扎耶德联邦研究生医学研究所皮肤科进行了一项准实验性横断面研究。从皮肤科门诊收集了200例临床诊断为扁平苔藓的病例以及同等数量据报道与乙肝病毒（HBV）感染无关的其他皮肤病患者（对照组）。采用酶联免疫吸附试验（ELISA）对他们进行乙肝表面抗原（HBsAg）筛查。使用SPSS 11版软件包进行统计分析。
每组200例患者中，3例扁平苔藓患者和7例对照组患者HBsAg呈阳性。比例显著性检验显示两组之间无显著差异（p>0.1）。
本研究未发现HBsAg携带者状态与扁平苔藓之间存在关联。
