扁平苔藓患者中乙肝表面抗原携带者状态的患病率——来自巴基斯坦拉合尔的200例报告

Prevalence of hepatitis B surface antigen carrier state in patients with lichen planus--report of 200 cases from Lahore, Pakistan.

作者信息

Mahboob Atiya, Haroon Tahir Saeed, Iqbal Zafar, Saleemi Munir Akhtar, Munir Asma

机构信息

Department of Dermatology, Shaikh Zayed Federal PGMI Lahore, Pakistan.

出版信息

J Ayub Med Coll Abbottabad. 2007 Oct-Dec;19(4):68-70.

PMID:18693602

Abstract

BACKGROUND

To determine the prevalence of hepatitis B surface antigen carrier state in patients with lichen planus.

METHODS

A quasi experimental cross sectional study was done at Department of Dermatology, Shaikh Zayed Federal Postgraduate Medical Institute, Lahore, Pakistan, from April 2003 to March 2005. Two hundred clinically diagnosed cases of LP and equal number of patients with other dermatoses not reportedly associated with hepatitis B virus (HBV) infection (control group) were collected from Skin Out Patient Department. They were screened for hepatitis B surface antigen (HBsAg) by Enzyme Linked Immunosorbent Assay (ELISA). Statistical analysis was done by using SPSS package version 11.

RESULTS

Out of 200 patients of each group, three patients with LP and seven patients from control group were positive for HBsAg. The test of significance for proportions revealed that there was no significant difference (p > 0.1) between two groups.

CONCLUSION

No association between HBsAg carrier state and LP was found in our study.

摘要

背景

确定扁平苔藓患者中乙肝表面抗原携带者状态的患病率。

方法

2003年4月至2005年3月在巴基斯坦拉合尔谢赫·扎耶德联邦研究生医学研究所皮肤科进行了一项准实验性横断面研究。从皮肤科门诊收集了200例临床诊断为扁平苔藓的病例以及同等数量据报道与乙肝病毒（HBV）感染无关的其他皮肤病患者（对照组）。采用酶联免疫吸附试验（ELISA）对他们进行乙肝表面抗原（HBsAg）筛查。使用SPSS 11版软件包进行统计分析。