Choudhury Ananyo, Lahiri Ansuman
Department of Biophysics, Molecular Biology and Genetics, University of Calcutta, 92 APC Road, Kolkata 700009, India.
Bioinformatics. 2008 Oct 1;24(19):2263-4. doi: 10.1093/bioinformatics/btn417. Epub 2008 Aug 11.
In the Arabidopsis thaliana regulatory element analyzer (AtREA) server, we have integrated sequence data, genome-wide expression data and functional annotation data in three application modules which will be useful to identify major regulatory targets of a user-provided cis-regulatory element (CRE), study different features of CRE distribution and evaluate the role of a set of CREs in the regulation of gene expression--independently as well as in combination with other user-provided CREs.
AtREA is freely available at http://www.bioinformatics.org/grn/atrea.html.
在拟南芥调控元件分析器(AtREA)服务器中,我们已将序列数据、全基因组表达数据和功能注释数据整合到三个应用模块中,这些模块将有助于识别用户提供的顺式调控元件(CRE)的主要调控靶点,研究CRE分布的不同特征,并评估一组CRE在基因表达调控中的作用——单独以及与其他用户提供的CRE组合时的作用。