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印度首例螺旋断层放射治疗实施的调强放射治疗个体化剂量测定——我们对50例患者的初步经验

Patient specific dosimetry for intensity-modulated radiotherapy delivered with first helical tomotherapy in India--our initial experience of 50 patients.

作者信息

Kinhikar R A, Master Z, Deshpande D D

机构信息

Tata Memorial Hospital, Parel, Mumbai, India.

出版信息

Australas Phys Eng Sci Med. 2008 Jun;31(2):139-45. doi: 10.1007/BF03178588.

DOI:10.1007/BF03178588
PMID:18697705
Abstract

Two-dimensional (2D) treatment verifications were performed for fifty patients planned and treated with helical tomotherapy (HT). The treatment verification consisted of an extended dose range (EDR2) film measurement as well as point dose measurements made with an A1SL ion chamber. The agreement between the calculated and the measured film dose distributions was evaluated with the gamma parameter calculated (3 mm and 3%). Good agreement was found between measured and calculated distributions with dose parameter registration using reference marks. The mean percent discrepancy for the point dose measurements was -0.4 (SD 1.4) for the high dose, low dose-gradient region. Thus the treatment verification results confirmed the safe delivery of the planned dose to the patient with helical tomotherapy.

摘要

对五十名接受螺旋断层放射治疗(HT)计划和治疗的患者进行了二维(2D)治疗验证。治疗验证包括扩展剂量范围(EDR2)胶片测量以及使用A1SL离子室进行的点剂量测量。使用计算出的伽马参数(3毫米和3%)评估计算剂量分布与测量胶片剂量分布之间的一致性。通过使用参考标记进行剂量参数配准,在测量和计算分布之间发现了良好的一致性。高剂量、低剂量梯度区域的点剂量测量平均百分比差异为-0.4(标准差1.4)。因此,治疗验证结果证实了螺旋断层放射治疗能向患者安全输送计划剂量。

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