Batey R G, Jones T, McAllister C
Drug and Alcohol Clinical Services, Hunter New England Area Health Service, Newcastle, New South Wales, Australia.
Int J Prison Health. 2008;4(3):156-63. doi: 10.1080/17449200802264712.
Prison populations in Western countries are characterised by a high hepatitis C prevalence. This reflects a high rate of imprisonment for drug related offences. Prison entrants who are HCV-negative face a significant risk of acquiring hepatitis C. Effective prevention strategies and successful treatment of a significant percentage of hepatitis C-positive inmates could reduce the risk of transmission in the prison context significantly. Several reports of treating hepatitis C in prisoners in major facilities have been published. We report our experience of establishing a liver clinic service in two regional prisons in New South Wales, Australia. Liver biopsy requirements to access treatment in Australia meant that only 46 of 196 reviewed patients were able to commence treatment in our 5-year experience. Treatment completion rate was 61% and end of treatment viral response was 57%. The removal of liver biopsy requirements in Australia in April 2006 has freed up access to treatment and our results encourage further effort to optimise the process of assessment and treatment in this high-risk population.
西方国家的监狱人口中丙型肝炎患病率很高。这反映出因与毒品相关犯罪而被监禁的比例很高。丙型肝炎病毒检测呈阴性的新入狱者面临感染丙型肝炎的重大风险。有效的预防策略以及对相当比例的丙型肝炎病毒检测呈阳性的囚犯的成功治疗,可显著降低监狱环境中的传播风险。已经发表了几篇关于在主要设施中治疗囚犯丙型肝炎的报告。我们报告了在澳大利亚新南威尔士州的两所地区监狱建立肝脏诊所服务的经验。在我们5年的经验中,由于澳大利亚获取治疗需要肝脏活检,在196名接受评估的患者中只有46人能够开始治疗。治疗完成率为61%,治疗结束时的病毒应答率为57%。2006年4月澳大利亚取消了肝脏活检要求,这使得更多人能够获得治疗,我们的结果鼓励进一步努力优化这一高风险人群的评估和治疗过程。