Kirkbride J B, Barker D, Cowden F, Stamps R, Yang M, Jones P B, Coid J W
University Department of Psychiatry, Addenbrooke's Hospital, Hills Road, Cambridge, UK.
Br J Psychiatry. 2008 Jul;193(1):18-24. doi: 10.1192/bjp.bp.107.041566.
Consistent observation of raised rates of psychoses among Black and minority ethnic (BME) groups may possibly be explained by their lower socio-economic status.
To test whether risk for psychoses remained elevated in BME populations compared with the White British, after adjustment for age, gender and current socio-economic status.
Population-based study of first-episode DSM-IV psychotic disorders, in individuals aged 18-64 years, in East London over 2 years.
All BME groups had elevated rates of a psychotic disorder after adjustment for age, gender and socio-economic status. For schizophrenia, risk was elevated for people of Black Caribbean (incidence rate ratios (IRR)=3.1, 95% CI 2.1-4.5) and Black African (IRR=2.6, 95% CI 1.8-3.8) origin, and for Pakistani (IRR=3.1, 95% CI 1.2-8.1) and Bangladeshi (IRR=2.3, 95% CI 1.1-4.7) women. Mixed White and Black Caribbean (IRR=7.7, 95% CI 3.2-18.8) and White Other (IRR=2.1, 95% CI 1.2-3.8) groups had elevated rates of affective psychoses (and other non-affective psychoses).
Elevated rates of psychoses in BME groups could not be explained by socio-economic status, even though current socio-economic status may have overestimated the effect of this confounder given potential misclassification as a result of downward social drift in the prodromal phase of psychosis. Our findings extended to all BME groups and psychotic disorders, though heterogeneity remains.
在黑人和少数族裔群体中,精神病发病率持续升高,这可能是由于他们较低的社会经济地位。
在调整年龄、性别和当前社会经济地位后,测试与英国白人相比,少数族裔群体中患精神病的风险是否仍然较高。
对东伦敦2年内年龄在18 - 64岁的首发DSM - IV精神病性障碍患者进行基于人群的研究。
在调整年龄、性别和社会经济地位后,所有少数族裔群体的精神病性障碍发病率均有所升高。对于精神分裂症,加勒比黑人(发病率比(IRR)= 3.1,95%置信区间2.1 - 4.5)和非洲黑人(IRR = 2.6,95%置信区间1.8 - 3.8)血统的人,以及巴基斯坦(IRR = 3.1,95%置信区间1.2 - 8.1)和孟加拉国(IRR = 2.3,95%置信区间1.1 - 4.7)女性的风险升高。白人加勒比黑人混血儿(IRR = 7.7,95%置信区间3.2 - 18.8)和其他白人(IRR = 2.1,95%置信区间1.2 - 3.8)群体的情感性精神病(以及其他非情感性精神病)发病率升高。
少数族裔群体中精神病发病率升高不能用社会经济地位来解释,尽管由于精神病前驱期的社会地位下降可能导致潜在的错误分类,当前社会经济地位可能高估了这个混杂因素的影响。我们的研究结果适用于所有少数族裔群体和精神病性障碍,尽管仍存在异质性。