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精神病、种族与社会经济地位。

Psychoses, ethnicity and socio-economic status.

作者信息

Kirkbride J B, Barker D, Cowden F, Stamps R, Yang M, Jones P B, Coid J W

机构信息

University Department of Psychiatry, Addenbrooke's Hospital, Hills Road, Cambridge, UK.

出版信息

Br J Psychiatry. 2008 Jul;193(1):18-24. doi: 10.1192/bjp.bp.107.041566.

Abstract

BACKGROUND

Consistent observation of raised rates of psychoses among Black and minority ethnic (BME) groups may possibly be explained by their lower socio-economic status.

AIMS

To test whether risk for psychoses remained elevated in BME populations compared with the White British, after adjustment for age, gender and current socio-economic status.

METHOD

Population-based study of first-episode DSM-IV psychotic disorders, in individuals aged 18-64 years, in East London over 2 years.

RESULTS

All BME groups had elevated rates of a psychotic disorder after adjustment for age, gender and socio-economic status. For schizophrenia, risk was elevated for people of Black Caribbean (incidence rate ratios (IRR)=3.1, 95% CI 2.1-4.5) and Black African (IRR=2.6, 95% CI 1.8-3.8) origin, and for Pakistani (IRR=3.1, 95% CI 1.2-8.1) and Bangladeshi (IRR=2.3, 95% CI 1.1-4.7) women. Mixed White and Black Caribbean (IRR=7.7, 95% CI 3.2-18.8) and White Other (IRR=2.1, 95% CI 1.2-3.8) groups had elevated rates of affective psychoses (and other non-affective psychoses).

CONCLUSIONS

Elevated rates of psychoses in BME groups could not be explained by socio-economic status, even though current socio-economic status may have overestimated the effect of this confounder given potential misclassification as a result of downward social drift in the prodromal phase of psychosis. Our findings extended to all BME groups and psychotic disorders, though heterogeneity remains.

摘要

背景

在黑人和少数族裔群体中,精神病发病率持续升高,这可能是由于他们较低的社会经济地位。

目的

在调整年龄、性别和当前社会经济地位后,测试与英国白人相比,少数族裔群体中患精神病的风险是否仍然较高。

方法

对东伦敦2年内年龄在18 - 64岁的首发DSM - IV精神病性障碍患者进行基于人群的研究。

结果

在调整年龄、性别和社会经济地位后,所有少数族裔群体的精神病性障碍发病率均有所升高。对于精神分裂症,加勒比黑人(发病率比(IRR)= 3.1,95%置信区间2.1 - 4.5)和非洲黑人(IRR = 2.6,95%置信区间1.8 - 3.8)血统的人,以及巴基斯坦(IRR = 3.1,95%置信区间1.2 - 8.1)和孟加拉国(IRR = 2.3,95%置信区间1.1 - 4.7)女性的风险升高。白人加勒比黑人混血儿(IRR = 7.7,95%置信区间3.2 - 18.8)和其他白人(IRR = 2.1,95%置信区间1.2 - 3.8)群体的情感性精神病(以及其他非情感性精神病)发病率升高。

结论

少数族裔群体中精神病发病率升高不能用社会经济地位来解释,尽管由于精神病前驱期的社会地位下降可能导致潜在的错误分类,当前社会经济地位可能高估了这个混杂因素的影响。我们的研究结果适用于所有少数族裔群体和精神病性障碍,尽管仍存在异质性。

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