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雷氏间隙的显微内镜检查

Microendoscopy of Reinke's space.

作者信息

Hoffman Henry T, Bock Jonathan M, Karnell Lucy Hynds, Ahlrichs-Hanson Janice

机构信息

Department of Otolaryngology-Head and Neck Surgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242-1078, USA.

出版信息

Ann Otol Rhinol Laryngol. 2008 Jul;117(7):510-4; discussion 515-6. doi: 10.1177/000348940811700707.

Abstract

OBJECTIVES

Contemporary surgical treatment of the superficial layer of the lamina propria or Reinke's space is most commonly performed through an incision in the overlying vocal fold epithelium. This approach may disrupt normal tissue, induce scarring, and allow extrusion of implanted materials. Previously reported external approaches to Reinke's space required either a laryngofissure or a "minithyrotomy" for access. These surgical approaches were performed without direct imaging of Reinke's space. Instruments placed below the vocal fold epithelium via this external approach were visualized through the translucent vocal fold epithelium. We designed this study to identify the feasibility of limited-access surgery of the lamina propria using microendoscopes placed into Reinke's space through an external approach.

METHODS

A cadaveric human larynx was dissected, and microendoscopes were directly advanced into Reinke's space through a subepithelial puncture of the cricothyroid membrane, as well as lateral fenestration through the thyroid cartilage.

RESULTS

Photodocumentation of the undersurface of vocal fold epithelium, the opposing surface of the vocal ligament, and the intervening Reinke's space was successfully accomplished.

CONCLUSIONS

Advances in both microendoscopes and accompanying instrumentation permit access to the superficial layer of the lamina propria without disrupting the overlying epithelium. This approach to microendoscopy of Reinke's space may allow for more effective surgical treatment of cysts, chronic edema, vascular abnormalities, atrophy, scarring, and sulcus vocalis.

摘要

目的

目前对固有层浅层或Reinke间隙的手术治疗最常通过覆盖其上的声带上皮切口进行。这种方法可能会破坏正常组织、导致瘢痕形成,并使植入材料挤出。先前报道的进入Reinke间隙的外部方法需要进行喉裂开术或“微型甲状腺切开术”。这些手术方法在没有对Reinke间隙进行直接成像的情况下进行。通过这种外部方法放置在声带上皮下方的器械通过半透明的声带上皮可见。我们设计本研究以确定通过外部方法将微型内镜放入Reinke间隙对固有层进行有限入路手术的可行性。

方法

解剖一具尸体人喉,通过环甲膜的上皮下穿刺以及通过甲状软骨的侧方开窗将微型内镜直接推进到Reinke间隙。

结果

成功完成了声带上皮下表面、声带韧带相对表面以及其间的Reinke间隙的摄影记录。

结论

微型内镜及其配套器械的进展使得在不破坏上方上皮的情况下能够进入固有层浅层。这种对Reinke间隙进行微型内镜检查的方法可能允许对囊肿、慢性水肿、血管异常、萎缩、瘢痕形成和声沟进行更有效的手术治疗。

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