Ma Janice, Vaillancourt Régis, Bennett Carol
Directorate of Medical Policy, Pharmacy Policies and Standards, National Defence Medical Centre Building, 2nd Floor, 1745 Alta Vista Drive, Ottawa, Ontario, K1A 0K6, Canada.
Mil Med. 2008 Jul;173(7):666-70. doi: 10.7205/milmed.173.7.666.
This study was performed to quantify adherence rates to lipid-lowering drug therapy among members of the Canadian Forces (CF) and to identify factors associated with nonadherence.
Pharmacy claims were reviewed for all CF members who received a lipid-lowering drug between April 1 and June 1, 2003. Subjects were categorized as adherent if records indicated consumption of at least 80% of prescribed doses. Logistic regression was performed to assess the impact of patient and drug characteristics upon adherence.
Overall adherence rate at 1 year was 38.5% among all users of lipid-lowering medications. Adherence did not vary among the different classes of lipid-lowering drugs. Duration of service was the only independent predictor of adherence.
Despite a relative lack of treatment barriers and the presence of established treatment programs in the CF health care system, long-term adherence with lipid-lowering medications remains suboptimal in this population.
本研究旨在量化加拿大军队（CF）成员降脂药物治疗的依从率，并确定与不依从相关的因素。
对2003年4月1日至6月1日期间接受降脂药物治疗的所有CF成员的药房报销记录进行审查。如果记录显示服用了至少80%的规定剂量，则将受试者归类为依从者。进行逻辑回归分析以评估患者和药物特征对依从性的影响。
所有降脂药物使用者的1年总体依从率为38.5%。不同类别的降脂药物之间的依从性没有差异。服役时间是依从性的唯一独立预测因素。
尽管CF医疗保健系统中相对缺乏治疗障碍且存在既定的治疗方案，但该人群中降脂药物的长期依从性仍然不理想。
