Cappuccio M, Gasbarrini A, Van Urk P, Bandiera S, Boriani S
Department of Orthopaedics and Traumatology, Spine Surgery, Ospedale Maggiore C.A. Pizzardi, Bologna, Italy.
Eur Rev Med Pharmacol Sci. 2008 May-Jun;12(3):155-60.
A retrospective clinical study was conducted to validating the treatment algorithm in patients with spinal metastasis. The study participants were 43 patients with spinal metastasis from carcinoma. Since most interventions are palliative we had to seek for clear definitions to describe the results, aiming to increase the quality of life. To this purpose, we would introduce the concept of "target achievement". We presume that the target is achieved when all the following findings are present: a survival rate which is not inferior to the average, improvement or the maintenance of the neurological condition and achievement of local control. The results of this study demonstrate that performing the treatment suggested by the algorithm, the majority of the patients have a good residual quality of life. Worse results are obtained when a more aggressive treatment is selected.
进行了一项回顾性临床研究，以验证脊柱转移瘤患者的治疗算法。研究参与者为43例癌性脊柱转移患者。由于大多数干预措施都是姑息性的，我们必须寻求明确的定义来描述结果，旨在提高生活质量。为此，我们将引入“目标达成”的概念。我们假定当出现以下所有情况时目标即达成：生存率不低于平均水平、神经状况得到改善或维持以及实现局部控制。本研究结果表明，按照该算法建议进行治疗，大多数患者具有良好的残余生活质量。选择更积极的治疗时，结果会更差。
