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内分泌胰岛素样生长因子-I(IGF-I)在雌性牛繁殖中的作用。

The role of endocrine insulin-like growth factor-I (IGF-I) in female bovine reproduction.

作者信息

Velazquez M A, Spicer L J, Wathes D C

机构信息

Escuela Superior de Ciencias Agropecuarias, Universidad Autónoma de Campeche, Calle 53 s/n, C.P. 24350, Escárcega, Campeche, Mexico.

出版信息

Domest Anim Endocrinol. 2008 Nov;35(4):325-42. doi: 10.1016/j.domaniend.2008.07.002. Epub 2008 Aug 8.

DOI:10.1016/j.domaniend.2008.07.002
PMID:18703307
Abstract

Insulin-like growth factor-I (IGF-I) plays a pivotal role in cattle fertility, acting as a monitoring signal that allows reproductive events to occur when nutritional conditions for successful reproduction are reached. However, endocrine IGF-I is not a predictor of reproductive events, but rather an indirect estimator of the suitability of the animal to achieve the reproductive event in question. Although measuring circulating IGF-I concentrations might not have any clinical application in the cattle industry, endocrine IGF-I screening will continue to be important for the study of interactions between nutrition and reproduction. In addition, endocrine IGF-I screening could be used as an ancillary test for the selection of cattle for high reproductive potential, especially in herds of high genetic merit for milk production, in which a decline in fertility has been identified.

摘要

胰岛素样生长因子-I(IGF-I)在牛的繁殖力中起着关键作用,它作为一种监测信号,当达到成功繁殖所需的营养条件时,促使生殖活动发生。然而,内分泌IGF-I并非生殖活动的预测指标,而是动物是否适合完成相关生殖活动的间接评估指标。尽管测量循环中IGF-I的浓度在养牛业可能没有任何临床应用价值,但内分泌IGF-I筛查对于研究营养与繁殖之间的相互作用仍将具有重要意义。此外,内分泌IGF-I筛查可作为一种辅助检测手段,用于选择具有高繁殖潜力的牛,特别是在已发现繁殖力下降的高遗传产奶性能牛群中。

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