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加巴喷丁用于难治性特发性三叉神经痛

Gabapentin for refractory idiopathic trigeminal neuralgia.

作者信息

Pandey Chandra Kant, Singh Namita, Singh Prabhat Kumar

机构信息

Department of Anaesthesiology and Critical Care Medicine, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow.

出版信息

J Indian Med Assoc. 2008 Feb;106(2):124-5.

Abstract

Trigeminal neuralgia is sudden, usually unilateral, severe, stabbing, brief recurrent pain in the distribution area of one or more of the branches of trigeminal nerve. Various pharmacological agents including carbamazepine, oxcarbazepine, phenytoin, lamotrigine, baclofen and clonazepam have been tried with variable success rate. Here a case of idiopathic trigeminal neuralgia is presented. The patient presented in the emergency room with severe pain in the distribution area of maxillary branch of trigeminal nerve, resistant to conventional pharmacotherapy, managed successfully with gabapentin without untoward side-effects.

摘要

三叉神经痛是一种突发的、通常为单侧的、严重的、刺痛性的、短暂复发性疼痛,位于三叉神经一个或多个分支的分布区域。包括卡马西平、奥卡西平、苯妥英钠、拉莫三嗪、巴氯芬和氯硝西泮在内的各种药物都曾被尝试使用,成功率各不相同。本文介绍了一例特发性三叉神经痛病例。该患者在急诊室表现为三叉神经上颌支分布区域的剧痛,对传统药物治疗无效,使用加巴喷丁成功治疗,且无不良副作用。

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