Intraductal oncocytic papillary neoplasm of the pancreas with strong accumulation on FDG-PET.

This paper reports a case of resected intraductal oncocytic papillary neoplasm (IOPN) of the pancreas. A 69-year-old woman was admitted with right hypochondriac pain. Ultrasonography, contrast-enhanced computed tomography and magnetic resonance imaging showed a cystic lesion, 10cm in diameter, in the head of the pancreas. The lesion contained a number of mural nodules 1cm in diameter with thick walls, which demonstrated hypervascularity. The main pancreatic duct was slightly dilated, 7mm in diameter. 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) showed very strong uptake in the thick wall and mural nodules of the tumor. Substomach-preserving pancreatoduodenectomy (SSPPD) was performed. The patient is presently alive and well without any evidence of recurrent disease 18 months after the operation. IOPN has the potential to develop into invasive carcinoma, and therefore, should be completely resected whenever possible.