Kato Yuichiro, Nakagouri Toshio, Konishi Masaru, Takahashi Shinichiro, Gotoda Naoto, Hasebe Takahiro, Kinosita Taira
Hepatobiliarypancreaic Surgery Division, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.
Hepatogastroenterology. 2008 May-Jun;55(84):900-2.
This paper reports a case of resected intraductal oncocytic papillary neoplasm (IOPN) of the pancreas. A 69-year-old woman was admitted with right hypochondriac pain. Ultrasonography, contrast-enhanced computed tomography and magnetic resonance imaging showed a cystic lesion, 10cm in diameter, in the head of the pancreas. The lesion contained a number of mural nodules 1cm in diameter with thick walls, which demonstrated hypervascularity. The main pancreatic duct was slightly dilated, 7mm in diameter. 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) showed very strong uptake in the thick wall and mural nodules of the tumor. Substomach-preserving pancreatoduodenectomy (SSPPD) was performed. The patient is presently alive and well without any evidence of recurrent disease 18 months after the operation. IOPN has the potential to develop into invasive carcinoma, and therefore, should be completely resected whenever possible.
本文报告一例经手术切除的胰腺导管内嗜酸性乳头状肿瘤（IOPN）。一名69岁女性因右季肋部疼痛入院。超声、增强计算机断层扫描和磁共振成像显示胰腺头部有一个直径10cm的囊性病变。该病变包含多个直径1cm的壁结节，壁增厚，表现为血管丰富。主胰管轻度扩张，直径7mm。18F-氟脱氧葡萄糖正电子发射断层扫描（FDG-PET）显示肿瘤厚壁和壁结节有非常强烈的摄取。行保留胃的胰十二指肠切除术（SSPPD）。患者术后18个月目前健在，无任何复发疾病迹象。IOPN有发展为浸润性癌的可能，因此，只要有可能，应进行完整切除。
