Hallay Judit, Micskei Cs, Fülesdi B, Kovács G, Szentkereszty Zs, Takács I, Sipka S, Bodolay E, Sápy P
Department of Anesthesiology & Intensive Care, University of Debrecen, Medical & Health Science Cente,r Debrecen, Hungary.
Hepatogastroenterology. 2008 May-Jun;55(84):1099-102.
BACKGROUND/AIMS: The advantages of jejunal nutrition in postoperative bowel paralysis following pancreato-duodenectomy were analyzed.
Patients resected for pancreatic cancer received 25 kcal/kg/day and were followed up for 10 days postoperatively. Nasojejunal tube ensured enteral feeding in 16 patients (Gr. I), 6 patients (Gr. II) were nourished parenterally. Laboratory parameters, outcome were compared. Bowel movements were registered. Patients of Gr.1 received 25 kcal/kg parenterally. Jejunal nutriment (1.5 cal/mL) followed gradually up to 1500mL. Parenteral nutriment decreased reflecting enteral intake. Patients of Gr. II were nourished parenterally only for 8 days. Laboratory data were measured preoperatively, on the 1st, 4th, 10th days.
The first stool appeared on the 4th day in Gr. I In Gr. II the bowel movement was delayed by 8 days. Laboratory data from the 1st, and 10th days were compared. In Gr. I serum total protein increased from 48.06 to 58.7g/L (p<0.001), serum albumin from 27.5 to 32.2g/L (p<0.02), CRP decreased from 117.8 to 74.1mg/L (p<0.035). No changes were significant in Gr. II. Length of hospitalization, weight loss did not differ between the 2 groups.
Immediately postoperative use of a three-luminal tube ensured early enteral nutrition, improved serum total protein, albumin values and facilitated bowel movements.
背景/目的:分析空肠营养在胰十二指肠切除术后肠麻痹中的优势。
因胰腺癌接受手术切除的患者,给予每日25千卡/千克的能量,并在术后随访10天。16例患者(I组)通过鼻空肠管进行肠内喂养,6例患者(II组)接受肠外营养。比较实验室参数和结果。记录排便情况。I组患者先接受每日25千卡/千克的肠外营养。随后逐渐给予空肠营养制剂(1.5千卡/毫升),直至1500毫升。随着肠内营养摄入量的增加,肠外营养量逐渐减少。II组患者仅接受8天的肠外营养。在术前、术后第1天、第4天和第10天测量实验室数据。
I组患者在术后第4天首次排便。II组患者排便延迟了8天。比较两组患者术后第1天和第10天的实验室数据。I组患者血清总蛋白从48.06克/升增至58.7克/升(p<0.001),血清白蛋白从27.5克/升增至32.2克/升(p<0.02),CRP从117.8毫克/升降至74.1毫克/升(p<0.035)。II组患者无显著变化。两组患者的住院时间和体重减轻情况无差异。
术后立即使用三腔管可确保早期肠内营养,改善血清总蛋白和白蛋白水平,并促进排便。