Cheguirián M L, Carvajal L R, Ledesma E M, Enrico M C, Reale A L, Culasso C, Bertoni L
Servicio de Bacteriología, Hospital de Niños de la Santísima Trinidad de Córdoba, Córdoba, Argentina.
Rev Argent Microbiol. 2008 Apr-Jun;40(2):111-5.
The purpose of our research was to know the frequency of microorganisms causing bacteremia and/or fungemia in oncology patients from Hospital de Niños de Córdoba, as well as to describe the antimicrobial susceptibility patterns of bacteria isolated from January 2006 to April 2007. A total of 59 bacteremia and fungemia cases in 44 patients were studied. From the total number of isolations, 45.8% were gram-negative bacilli, 35.6% were gram-positive cocci, and 18.6% were yeasts. The global distribution of the most prevalent microorganisms was the following: Klebsiella spp. 15.3%; Staphylococcus aureus and Candida parapsilosis 11.9%; coagulase-negative staphylococci 10.2%; Escherichia coli 8.5%, and Pseudomonas aeruginosa 6.8%. More than 40% (41.2%) of enterobacteria showed an extended-spectrum beta-lactamase phenotype, and 20.0% of non-fermenting gram-negative bacilli were multi-resistant to tested antibiotics, while 38.5% of Staphylococcus spp. were methicillin-resistant. In conclusion, the most prevalent microorganisms were gram-negative bacilli, and within this group, enterobacteria evidenced a higher percentage of resistance to tested antibiotics.
我们研究的目的是了解科尔多瓦儿童医院肿瘤患者中引起菌血症和/或真菌血症的微生物频率，以及描述2006年1月至2007年4月分离出的细菌的抗菌药敏模式。共研究了44例患者中的59例菌血症和真菌血症病例。在所有分离菌株中，45.8%为革兰氏阴性杆菌，35.6%为革兰氏阳性球菌，18.6%为酵母菌。最常见微生物的总体分布如下：克雷伯菌属15.3%；金黄色葡萄球菌和近平滑念珠菌11.9%；凝固酶阴性葡萄球菌10.2%；大肠杆菌8.5%，铜绿假单胞菌6.8%。超过40%（41.2%）的肠杆菌表现出超广谱β-内酰胺酶表型，20.0%的非发酵革兰氏阴性杆菌对测试抗生素多重耐药，而38.5%的葡萄球菌属对甲氧西林耐药。总之，最常见的微生物是革兰氏阴性杆菌，在这一组中，肠杆菌对测试抗生素的耐药率更高。
