Cao Zheng, Zhou Yu-jie, Zhao Ying-xin, Liu Yu-yang, Shi Dong-mei, Guo Yong-he, Cheng Wan-jun, Nie Bin, Wang Jian-long
Department of Cardiology, Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing 100029, China.
Chin Med J (Engl). 2008 Jun 20;121(12):1126-9.
The radial artery is currently regarded as a useful vascular access site for coronary procedures. This study was conducted to investigate the feasibility and safety of the percutaneous radial artery approach for angioplasty in the elderly.
Two thousand and fifty-eight consecutive patients (762 elderly, age = 65 years; and 1296 non-elderly, age < 65 years, respectively) who underwent transradial coronary angioplasty were recruited in this study. Study endpoints included procedure success rate, procedure time, vascular complications at access site, and major adverse cardiac and cerebrovascular events during hospitalization.
Elderly patients were more likely to present with unstable angina and renal dysfunction. The incidence of radial and brachiocephalic trunk anatomical tortuosity was higher in elderly patients than that in non-elderly patients (11.5% vs 3.7%; 8.9% vs 2.6%, P < 0.01, respectively). However, procedural success rate (94.7% vs 95.6%) and total mean procedure time ((67.9 +/- 27.3) minutes vs (58.6 +/- 38.5) minutes) for transradial coronary angioplasty were not significantly different between the two groups. Clinical course during the hospitalization was slightly worse in the elderly patients because of more adverse cardiac and cerebrovascular events after the procedure. However, the incidence of vascular complications was not significantly different between the elderly and non-elderly patients.
Although the incidence of radial and brachiocephalic trunk anatomical tortuosity is higher in elderly patients, transradial coronary intervention can be performed with similar safety and procedural success in these patients as compared with non-elderly patients.
目前桡动脉被视为冠状动脉介入手术中一个有用的血管穿刺部位。本研究旨在探讨经皮桡动脉途径对老年患者进行血管成形术的可行性和安全性。
本研究纳入了2058例连续接受经桡动脉冠状动脉成形术的患者(分别为762例老年患者,年龄≥65岁;以及1296例非老年患者,年龄<65岁)。研究终点包括手术成功率、手术时间、穿刺部位的血管并发症以及住院期间主要的不良心脑血管事件。
老年患者更易出现不稳定型心绞痛和肾功能不全。老年患者桡动脉和头臂干解剖学迂曲的发生率高于非老年患者(分别为11.5%对3.7%;8.9%对2.6%,P<0.01)。然而,两组经桡动脉冠状动脉成形术的手术成功率(94.7%对95.6%)和总平均手术时间((67.9±27.3)分钟对(58.6±38.5)分钟)并无显著差异。老年患者住院期间的临床过程稍差,因为术后不良心脑血管事件较多。然而,老年患者与非老年患者血管并发症的发生率并无显著差异。
尽管老年患者桡动脉和头臂干解剖学迂曲的发生率较高,但与非老年患者相比,这些患者进行经桡动脉冠状动脉介入治疗的安全性和手术成功率相似。