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妊娠期间因过量摄入碳酸钙抗酸剂(乳-碱综合征)引发的高钙血症危象:经血液透析成功治疗

Hypercalcemic crisis in pregnancy associated with excessive ingestion of calcium carbonate antacid (milk-alkali syndrome): successful treatment with hemodialysis.

作者信息

Kleinman G E, Rodriquez H, Good M C, Caudle M R

机构信息

Department of Obstetrics and Gynecology, University of Tennessee Medical Center, Knoxville.

出版信息

Obstet Gynecol. 1991 Sep;78(3 Pt 2):496-9.

PMID:1870805
Abstract

Severe hypercalcemia, a potentially life-threatening condition, has been reported rarely during pregnancy. A patient with hypercalcemic crisis associated with excessive ingestion of absorbable calcium antacid was treated successfully with hemodialysis as well as other therapeutic measures, such as saline diuresis. This acute therapy resulted in long-term normalization of maternal calcium levels. The fetus, who exhibited a low biophysical score during the initial admission, was delivered a month later and had an uncomplicated neonatal course. Acute hemodialysis can be an effective, rapid, and safe method of lowering serum calcium levels in pregnant patients with severe hypercalcemia unresponsive to other medical therapies.

摘要

严重高钙血症是一种可能危及生命的疾病,在孕期很少有报道。一名因过量摄入可吸收性钙抗酸剂而发生高钙血症危象的患者,通过血液透析以及其他治疗措施(如生理盐水利尿)成功得到治疗。这种急性治疗使母体钙水平长期恢复正常。最初入院时生物物理评分较低的胎儿,一个月后分娩,新生儿期过程顺利。对于其他药物治疗无效的重度高钙血症孕妇,急性血液透析可能是一种有效、快速且安全的降低血清钙水平的方法。

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