Rovner Joshua, Yaghoobian Arash, Gott Michael, Tindel Nathaniel
Department of Orthopaedic Surgery, Montefiore Medical Center, Bronx, NY, USA.
Spine (Phila Pa 1976). 2008 Aug 15;33(18):E656-8. doi: 10.1097/BRS.0b013e31817eb85a.
Case report of Pigmented Villonodular Synovitis (PVNS) of a lumbar facet joint which presented as an incidental finding of an expansile lytic lesion of the L5 lamina.
Exceedingly rare is the case of PVNS affecting the zygoapophyseal (facet) joints of the spine. To our knowledge only 30 cases have to this point been reported. We will discuss clinical presentation, diagnostic workup, treatment, and follow-up of this rare case that was treated at our institution.
First described by Jaffe et al in 1941, PVNS is a relatively uncommon benign disorder of unknown etiology that is characterized by progressive synovial proliferation. Benign, but locally aggressive, it is found most commonly in the knee and other large joints. PVNS affecting the zygoapophyseal (facet) joints of the spine is extremely rare, and in our opinion suitable for reporting.
The physical examination of this patient showed signs and symptoms that prompted the need for a plain radiographs and subsequently magnetic resonance imaging (MRI). MRI showed evidence of a lesion in the right lamina of L5. After follow-up MRI showed an expanding lesion, and CT scan confirmed the lytic nature of the lesion, it was decided that an excisional biopsy was warranted. RESULTS.: Postoperative clinical course was unremarkable. The patient was ambulating the next day and was discharged home 2 days later without neurologic deficit or local wound problems. On office follow-up, the patient continued to have diffuse, vague low back pain. Repeat radiograph examination shows no further boney destruction. Repeat MRI shows no residual lesion.
We have learned from this case that PVNS of the facet joint, although exceedingly rare must be considered as a possible cause of expanding lytic lesions of the spine.
腰椎小关节色素沉着绒毛结节性滑膜炎(PVNS)病例报告,该病例为偶然发现的L5椎板膨胀性溶骨性病变。
PVNS累及脊柱关节突(小关节)极为罕见。据我们所知,到目前为止仅报道了30例。我们将讨论在我们机构治疗的这一罕见病例的临床表现、诊断检查、治疗及随访情况。
PVNS于1941年由贾菲等人首次描述,是一种病因不明的相对罕见的良性疾病,其特征为滑膜进行性增生。该疾病虽为良性,但具有局部侵袭性,最常见于膝关节和其他大关节。PVNS累及脊柱关节突(小关节)极为罕见,我们认为适合予以报道。
该患者的体格检查显示出的体征和症状促使其进行了X线平片及随后的磁共振成像(MRI)检查。MRI显示L5右侧椎板有病变迹象。随访MRI显示病变扩大,CT扫描证实了病变的溶骨性,遂决定进行切除活检。结果:术后临床过程平稳。患者术后第二天即可行走,两天后出院,无神经功能缺损或局部伤口问题。门诊随访时,患者仍有弥漫性、模糊不清的下腰痛。复查X线片未显示进一步的骨质破坏。复查MRI未显示残留病变。
我们从该病例中了解到,小关节PVNS尽管极为罕见,但必须被视为脊柱膨胀性溶骨性病变的可能病因之一。