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腰椎小关节色素沉着绒毛结节性滑膜炎

Pigmented villonodular synovitis of a lumbar intervertebral facet joint.

作者信息

Müslüman Ahmet Murat, Cavuşoğlu Halit, Yilmaz Adem, Dalkiliç Türker, Tanik Canan, Aydin Yunus

机构信息

Neurosurgery Clinic, Sişli Etfal Education and Research Hospital, Istanbul, Turkey.

出版信息

Spine J. 2009 Aug;9(8):e6-9. doi: 10.1016/j.spinee.2008.12.010. Epub 2009 Mar 20.

Abstract

BACKGROUND CONTEXT

Pigmented villonodular synovitis (PVNS) is a slowly progressive lesion of uncertain etiology that involves the synovial membrane of joints or tendon sheaths. Only rarely does PVNS affect the axial skeleton, where it arises from the vertebral articular facet joint. Its treatment and prognosis remains limited.

PURPOSE

To describe our management in a patient with PVNS and to review previously published cases.

STUDY DESIGN

Case report.

METHODS

This is a case report of a 59-year-old woman who presented left sciatica. Computed tomography (CT) imaging revealed a mixed sclerotic and lucent lesion affecting the left L4-L5 facet joint. Magnetic resonance imaging (MRI) demonstrated a diffusely infiltrative process that originated from the left inferior articular process of L4 vertebra with extension into the spinal canal. A total synovectomy with left L4 hemilaminectomy was performed. Left L5 root was decompressed with total microscopic tumor removal. Decompression of spinal canal and absence of the tumor was shown by MRI and CT scan after the operation.

RESULTS

Complete resolution of the patient's complaints was achieved. Histopathological analysis was consistent with a diagnosis of PVNS.

CONCLUSIONS

The principle of surgical management of spinal lesions causing neurologic deficit is early surgical decompression. It is also important to totally remove the synovium, the origin of PVNS, to prevent the recurrence.

摘要

背景

色素沉着绒毛结节性滑膜炎(PVNS)是一种病因不明的缓慢进展性病变,累及关节或腱鞘的滑膜。PVNS极少累及中轴骨骼,若累及则起源于椎体关节突关节。其治疗方法及预后有限。

目的

描述我们对一名PVNS患者的治疗情况,并回顾既往发表的病例。

研究设计

病例报告。

方法

本病例报告为一名59岁出现左侧坐骨神经痛的女性患者。计算机断层扫描(CT)成像显示左侧L4-L5关节突关节有硬化与透亮混合性病变。磁共振成像(MRI)显示为弥漫性浸润性病变,起源于L4椎体左侧下关节突并延伸至椎管。实施了全滑膜切除术及左侧L4半椎板切除术。通过全显微镜下肿瘤切除对左侧L5神经根进行减压。术后MRI和CT扫描显示椎管减压且无肿瘤残留。

结果

患者症状完全缓解。组织病理学分析与PVNS诊断相符。

结论

对于导致神经功能缺损的脊柱病变,手术治疗的原则是早期手术减压。彻底切除PVNS起源的滑膜以防止复发也很重要。

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