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腰腹分流术治疗强直性脊柱炎硬脊膜扩张症

Lumboperitoneal shunt for treatment of dural ectasia in ankylosing spondylitis.

作者信息

Dinichert A, Cornelius J F, Lot G

机构信息

Neurosurgery, Hôpital Lariboisière, 2 rue Ambroise Paré, 75010 Paris, France.

出版信息

J Clin Neurosci. 2008 Oct;15(10):1179-82. doi: 10.1016/j.jocn.2007.09.003. Epub 2008 Aug 16.

Abstract

Neurological complications of ankylosing spondylitis (AS) are reported in 2.1% of patients. Cauda equina syndrome (CES) is rare and occurs at the ankylosing stage. MRI and CT of the lumbar spine show a cauda equina deformation with dural ectasia and bony erosion. We report three patients with AS presenting with progressive CES. These patients underwent lumboperitoneal shunting (LPS) surgery. The motor deficit improved in all cases. We suggest that CES develops from arterial pulsation of the CSF on a dural sac with reduced elasticity and that LPS reduces these intradural pressure shock waves. A meta-analysis by Ahn et al. [Ahn NU, Ahn UM, Nallamshetty L, et al. Cauda equina syndrome in ankylosing spondylitis (the CES-AS syndrome): meta-analysis of outcomes after medical and surgical treatments. J Spinal Disord 2001;14:427-33] concludes that surgical treatment has a better outcome than conservative or no treatment. Adding our 3 patients to this analysis, it appears that LPS for CES in AS is more efficient than laminectomy. LPS is a routine procedure for a rare indication, which promises improvement or atleast a stabilization of this disabling evolution of the disease.

摘要

据报道,强直性脊柱炎(AS)患者中神经并发症的发生率为2.1%。马尾综合征(CES)较为罕见,发生于强直性脊柱炎阶段。腰椎的MRI和CT显示马尾变形伴硬脊膜扩张和骨质侵蚀。我们报告了3例出现进行性CES的AS患者。这些患者接受了腰大池-腹腔分流术(LPS)。所有病例的运动功能障碍均有改善。我们认为,CES是由于脑脊液在弹性降低的硬脊膜囊上的动脉搏动所致,而LPS可减少这些硬膜内压力冲击波。Ahn等人的一项荟萃分析[Ahn NU, Ahn UM, Nallamshetty L, et al. Cauda equina syndrome in ankylosing spondylitis (the CES-AS syndrome): meta-analysis of outcomes after medical and surgical treatments. J Spinal Disord 2001;14:427-33]得出结论,手术治疗比保守治疗或不治疗效果更好。将我们的3例患者纳入该分析后,似乎AS患者CES行LPS手术比椎板切除术更有效。LPS是一种针对罕见适应症的常规手术,有望改善或至少稳定这种致残性疾病的进展。

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