Baldisserotto Matteo, Valduga Simone G, da Cunha Carol Fernandes Jerzewski Sotero
Department of Radiology, Hospital São Lucas, Brazil.
Radiology. 2008 Oct;249(1):278-84. doi: 10.1148/radiol.2491071703. Epub 2008 Aug 18.
To evaluate asymptomatic children and adolescents to determine the rate of detection of the normal appendix at unenhanced magnetic resonance (MR) imaging.
This study was approved by the medical ethics committees of the authors' institutions, and informed consent was obtained from participants' parents or guardians. Forty asymptomatic volunteers underwent MR imaging to detect the appendix. Mean age (+/- standard deviation) for the 18 boys was 12.8 years +/- 2.4 (range, 9-17 years) and for the 22 girls was 12.7 years +/- 2.7 (range, 8-17 years). The MR imaging protocol consisted of axial T1-weighted fast spin-echo (SE), axial and coronal T2-weighted fast SE, and axial T2-weighted fat-saturated fast SE sequences. Two observers interpreted results independently, and kappa coefficients were calculated to evaluate agreement. The rate of detection was defined as the percentage of times that the appendix was visualized with at least one sequence. Body mass index was recorded for all participants.
The normal appendix was detected by one observer in 19 cases (48%) and by the other in 20 cases (50%). The rate of appendix detection after observers reached a consensus was 48% (95% confidence interval: 32%, 64%). Interobserver agreement for appendix detection was good for most sequences analyzed. The greatest rate of normal appendix detection was found with the axial T2-weighted fast SE sequence (48%).
The rate of normal appendix detection in children and adolescents at unenhanced MR imaging was 48%, which is similar to computed tomographic but lower than ultrasonographic detection rates.
评估无症状儿童和青少年，以确定在非增强磁共振（MR）成像中正常阑尾的检出率。
本研究经作者所在机构的医学伦理委员会批准，并获得参与者父母或监护人的知情同意。40名无症状志愿者接受MR成像以检测阑尾。18名男孩的平均年龄（±标准差）为12.8岁±2.4（范围9 - 17岁），22名女孩的平均年龄为12.7岁±2.7（范围8 - 17岁）。MR成像方案包括轴位T1加权快速自旋回波（SE）、轴位和冠状位T2加权快速SE以及轴位T2加权脂肪抑制快速SE序列。两名观察者独立解读结果，并计算kappa系数以评估一致性。检出率定义为阑尾在至少一个序列中显影的次数百分比。记录所有参与者的体重指数。
一名观察者在19例（48%）中检测到正常阑尾，另一名观察者在20例（50%）中检测到。观察者达成共识后的阑尾检出率为48%（95%置信区间：32%，64%）。对于大多数分析的序列，观察者之间在阑尾检测方面的一致性良好。在轴位T2加权快速SE序列中正常阑尾的检出率最高（48%）。
在非增强MR成像中，儿童和青少年正常阑尾的检出率为48%，这与计算机断层扫描相似，但低于超声检查的检出率。
