Vetrichevvel Thirthar Palanivelu, Pise Gajanan A, Thappa Devinder Mohan
Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India.
Lepr Rev. 2008 Jun;79(2):193-5.
Thalidomide is the drug of choice in the treatment of severe erythema nodosum leprosum (ENL) in men. It has recently been associated with deep venous thrombosis (DVT) when used in treatment of refractory multiple myeloma along with combination chemotherapy. We report a case of DVT in a patient treated for ENL with corticosteroids and thalidomide, and suggest a possible mechanism for the association.
沙利度胺是男性严重麻风结节性红斑(ENL)治疗的首选药物。最近,它在与联合化疗用于治疗难治性多发性骨髓瘤时与深静脉血栓形成(DVT)有关。我们报告了一例用皮质类固醇和沙利度胺治疗ENL的患者发生DVT的病例,并提出了这种关联的一种可能机制。