Jenkins Alicia, Zhang Sarah X, Gosmanova Albina, Aston Christopher, Dashti Azar, Baker Mary Zoe, Lyons Timothy, Ma Jian-Xing
Department of Medicine, Endocrinology, Harold Hamm Oklahoma Diabetes Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Diabetes Res Clin Pract. 2008 Oct;82(1):e5-7. doi: 10.1016/j.diabres.2008.06.019. Epub 2008 Aug 19.
Serum PEDF levels (mean (S.D.)) were increased in 96 Type 2 diabetic vs. 54 non-diabetic subjects; 5.3 (2.8) vs. 3.2 (2.0)mug/ml, p<0.001. In diabetes, PEDF correlated with BMI, serum creatinine and LDL-cholesterol, but not with other lipids, HbA1c or CRP. PEDF did not differ by drugs, complications, or gender.
96名2型糖尿病患者的血清色素上皮衍生因子（PEDF）水平（均值（标准差））升高，而54名非糖尿病受试者则未升高；分别为5.3（2.8）与3.2（2.0）微克/毫升，p<0.001。在糖尿病患者中，PEDF与体重指数、血清肌酐和低密度脂蛋白胆固醇相关，但与其他血脂、糖化血红蛋白或C反应蛋白无关。PEDF在药物、并发症或性别方面无差异。
